Cure My Disease

Don't miss your cure!

 Log in / Sign up

Can Low-Dose combo tame tough blood pressure in kidney disease?

NCT ID NCT07645300

Not yet recruiting Disease control Sponsor: VA Office of Research and Development Source: ClinicalTrials.gov ↗

First seen Jun 12, 2026 · Last updated Jun 16, 2026 · Updated 2 times

Summary

This study looks at whether low doses of two older blood pressure drugs, spironolactone and chlorthalidone, can safely lower blood pressure in people with moderate to advanced chronic kidney disease (CKD). About 160 U.S. Veterans with CKD and high blood pressure will take the drugs alone or together for up to 12 weeks. The goal is to find effective treatment options that manage blood pressure without causing dangerous side effects like high potassium levels.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for HYPERTENSION TREATED WITH ANTIHYPERTENSIVE DRUGS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Richard L. Roudebush VA Medical Center, Indianapolis, IN

    Indianapolis, Indiana, 46202-2884, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.

CHRONIC KIDNEY DISEASE, 3B AND 4 HYPERTENSION TREATED WITH ANTIHYPERTENSIVE DRUGS