HIV-Positive livers for HIV-Positive patients: a new hope?

NCT ID NCT07665372

Not yet recruiting Disease control Sponsor: Johns Hopkins University Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether people with HIV who need a liver transplant can safely receive a liver from a donor who also had HIV. Researchers will compare infections and cancer rates between those who get an HIV-positive donor liver and those who get an HIV-negative donor liver. The goal is to see if using HIV-positive organs is a safe option to help more people get transplants faster.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: liver transplant from a donor with HIV
What this could lead to: If successful, this could show that using livers from HIV-positive donors is safe and effective for people with HIV, expanding the donor pool and reducing wait times.
What could go wrong: This is an observational study, not a treatment trial, so it won't directly improve health. There may be higher risks of infections or cancer in recipients of HIV-positive donor livers.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

HIV infectious disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HIV

Contacts and locations

Locations

Cedars-Sinai Medical Center

Los Angeles, California, 90048, United States
Emory University

Atlanta, Georgia, 30322, United States
Houston Methodist Research Institute

Houston, Texas, 77030, United States
Icahn School of Medicine at Mount Sinai

New York, New York, 10029, United States
Johns Hopkins University

Baltimore, Maryland, 21205, United States
Massachusetts General Hospital

Boston, Massachusetts, 02114, United States
Mayo Clinic, Arizona

Phoenix, Arizona, 85054, United States
Mayo Clinic, Florida

Jacksonville, Florida, 32224, United States
New York University School of Medicine

New York, New York, 10016, United States
Northwestern University

Chicago, Illinois, 60611, United States
Ochsner Clinic Foundation

Jefferson, Louisiana, 70121, United States
Ohio State University Medical Center

Columbus, Ohio, 43210, United States
University of California, San Francisco

San Francisco, California, 94143, United States
University of Cincinnati

Cincinnati, Ohio, 45229, United States
University of Colorado Anschutz

Aurora, Colorado, 80045, United States
University of Miami, Miami Transplant Institute

Miami, Florida, 33136, United States
University of Pittsburgh Medical Center

Pittsburgh, Pennsylvania, 15224, United States
University of Texas Southwestern Medical Center

Dallas, Texas, 75390, United States
Weill Cornell Medical College

New York, New York, 10065, United States

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