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Liver isolation chemo trial halted early – too few patients to draw conclusions

NCT ID NCT04701281

Terminated Disease control Sponsor: AllVascular Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This early-phase trial tested a new way to deliver chemotherapy directly to liver tumors that spread from colorectal cancer. Doctors used balloon catheters to isolate the liver's blood supply and then infused oxaliplatin, along with oral capecitabine. Only 5 people took part before the study was stopped, so we cannot say whether this approach is safe or effective.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
oxaliplatin and capecitabine
What this could lead to
If it works, this could offer a more targeted way to deliver chemotherapy to liver tumors, potentially reducing side effects from whole-body chemo.
What could go wrong
This was a very small, early-phase trial that was terminated early, so we don't have enough data to know if it's safe or effective. The procedure also involves isolating blood flow to the liver, which carries risks.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

malignant colon neoplasm metastasis from malignant tumor of colon Neoplasm Metastasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LIVER METASTASIS COLON CANCER

Contacts and locations

Locations

  • GenesisCare, St Leonards

    Saint Leonards, New South Wales, 2065, Australia

  • Gold Coast Private Hospital

    Southport, Queensland, 4215, Australia

  • Lake Macquarie Private Hospital

    Gateshead, New South Wales, 2290, Australia

  • Sydney Adventist Hospital

    Sydney, New South Wales, 2076, Australia

  • Sydney Southwest Private Hospital

    Sydney, New South Wales, 2170, Australia

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