Liver isolation chemo trial halted early – too few patients to draw conclusions
NCT ID NCT04701281
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This early-phase trial tested a new way to deliver chemotherapy directly to liver tumors that spread from colorectal cancer. Doctors used balloon catheters to isolate the liver's blood supply and then infused oxaliplatin, along with oral capecitabine. Only 5 people took part before the study was stopped, so we cannot say whether this approach is safe or effective.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
oxaliplatin and capecitabine
What this could lead to
If it works, this could offer a more targeted way to deliver chemotherapy to liver tumors, potentially reducing side effects from whole-body chemo.
What could go wrong
This was a very small, early-phase trial that was terminated early, so we don't have enough data to know if it's safe or effective. The procedure also involves isolating blood flow to the liver, which carries risks.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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GenesisCare, St Leonards
Saint Leonards, New South Wales, 2065, Australia
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Gold Coast Private Hospital
Southport, Queensland, 4215, Australia
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Lake Macquarie Private Hospital
Gateshead, New South Wales, 2290, Australia
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Sydney Adventist Hospital
Sydney, New South Wales, 2076, Australia
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Sydney Southwest Private Hospital
Sydney, New South Wales, 2170, Australia