15,000 patients enrolled in quest to cut liver cancer from hepatitis b

NCT ID NCT07169656

Recruiting now Knowledge-focused Sponsor: The First Affiliated Hospital of Zhengzhou University Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This real-world study is following 15,000 people with chronic hepatitis B across 200 hospitals in China. Researchers are comparing how well different antiviral drugs and interferon injections work to prevent liver cancer and improve long-term health. The goal is to find the best treatment strategies and move closer to a functional cure for hepatitis B.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: entecavir, tenofovir disoproxil fumarate, tenofovir alafenamide fumarate, tenofovir amibufenamide, peginterferon alfa-2b
What this could lead to: If successful, this study could provide clear evidence on which hepatitis B treatments best lower liver cancer risk, helping doctors choose the most effective therapy for each patient.
What could go wrong: This is an observational study, not a controlled trial, so results may be influenced by factors other than the treatments. It also only looks at current standard drugs, not new experimental options.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

chronic hepatitis B virus infection hepatitis B virus infection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHRONIC HEPATITIS B

Contacts and locations

Locations

Anyang District Hospital
RECRUITING

Pujiang, China
Bo'ai County People's Hospital
RECRUITING

Jiaozuo, China
Changge People's Hospital
RECRUITING

Xuchang, China
Changyuan County People's Hospital
RECRUITING

Xinxiang, China
Chinese Medicine Hospital of puyang
RECRUITING

Pujiang, China
Chinese People's Liberation Army Joint Logistics Support Force 970 Hospital,
RECRUITING

Yantai, China
Dancheng County People's Hospital
RECRUITING

Zhoukou, China
Dengzhou Central Hospital
RECRUITING

Nanyang, China
Dengzhou People's Hospital
RECRUITING

Nanyang, China
Fangcheng County People's Hospital
RECRUITING

Nanyang, China
Fanxian People's Hospital
RECRUITING

Pujiang, China
Fugou County People's Hospital
RECRUITING

Zhoukou, China
General Hospital Of Pingmei Shenma Group
RECRUITING

Pingdingshan, China
Gongyi City People's Hospital
RECRUITING

Zhengzhou, China
Guangshan County People's Hospital
RECRUITING

Xinyang, China
Guangzhou First People's Hospital
RECRUITING

Guangzhou, China
Gushi County People's Hospital
RECRUITING

Xinyang, China
Hebi Coal Mining Group General Hospital
RECRUITING

Hebi, China
Hebi Infectious Disease Hospital
RECRUITING

Hebi, China
Huaibin County People's Hospital
RECRUITING

Xinyang, China
Huaihe Hospital of Henan University
RECRUITING

Kaifeng, China
Huangchuan County People's Hospital
RECRUITING

Xinyang, China
Huanghe Sanmenxia Hospital
RECRUITING

Sanmenxia, China
Huaxian People's Hospital
RECRUITING

Anyang, China
Huixian People's Hospital
RECRUITING

Xinxiang, China
Infectious Diseases Hospital of Kaifeng
RECRUITING

Kaifeng, China
Jiaozuo People's Hospital
RECRUITING

Yantai, China
Jiyang County Hospital of Traditional Chinese Medicine
RECRUITING

Jinan, China
Jiyuan People's Hospital
RECRUITING

Jiyuan, China
Jiyuan Traditional Chinese Medicine Hospital
RECRUITING

Jiyuan, China
Junxian County People's Hospital
RECRUITING

Hebi, China
Kaifeng Central Hospital
RECRUITING

Kaifeng, China
Kaifeng Hospital of Traditional Chinese Medicine
RECRUITING

Kaifeng, China
Lankao First Hospital Group
RECRUITING

Kaifeng, China
Linyi Hospital of Traditional Chinese Medicine
RECRUITING

Linyi, China
Linyi People's Hospital
RECRUITING

Linyi, China
Linying County People's Hospital
RECRUITING

Luohe, China
Linzhou City People's Hospital
RECRUITING

Anyang, China
Luanchuan County People's Hospital
RECRUITING

Luoyang, China
Luohe Central Hospital
RECRUITING

Luohe, China
Luoning County People's Hospital
RECRUITING

Luoyang, China
Luoshan County People's Hospital
RECRUITING

Xinyang, China
Luoyang Central Hospital
RECRUITING

Luoyang, China
Luoyang First People's Hospital
RECRUITING

Luoyang, China
Luoyang Third People's Hospital
RECRUITING

Luoyang, China
Lushan County People's Hospital
RECRUITING

Pingdingshan, China
Mengzhou Hospital of Traditional Chinese Medicine
RECRUITING

Jiaozuo, China
Minquan County Hospital of Traditional Chinese Medicine
RECRUITING

Shangqiu, China
Minquan County People's Hospital
RECRUITING

Shangqiu, China
Nanle County People's Hospital
RECRUITING

Pujiang, China
Nanyang Central Hospital
RECRUITING

Nanyang, China
Nanyang First People's Hospital
RECRUITING

Nanyang, China
Nanyang Oilfield General Hospital
RECRUITING

Nanyang, China
Nanyang Second General Hospital
RECRUITING

Nanyang, China
Nanzhao County People's Hospital
RECRUITING

Nanyang, China
Neihuang County People's Hospital
RECRUITING

Anyang, China
Neixiang County People's Hospital
RECRUITING

Nanyang, China
Ningbo Medical Center Iihuili hospital
RECRUITING

Ningbo, China
People's Hospital of Baofeng
RECRUITING

Pingdingshan, China
People's Hospital of Queshan
RECRUITING

Zhumadian, China
People's Hospital of Rizhao
RECRUITING

Rizhao, China
Pingdingshan First People's Hospital
RECRUITING

Pingdingshan, China
Pingdu Municipal People's Hospital
RECRUITING

Pingdu, China
Pingyu County People's Hospital
RECRUITING

Zhumadian, China
Puyang People's Hospital
RECRUITING

Pujiang, China
Qinyang People's Hospital
RECRUITING

Jiaozuo, China
Qixian People's Hospital
RECRUITING

Kaifeng, China
Runan County Hospital of Traditional Chinese Medicine
RECRUITING

Zhumadian, China
Ruyang County People's Hospital
RECRUITING

Luoyang, China
Ruzhou First People's Hospital
RECRUITING

Pingdingshan, China
Sanmenxia Central Hospital
RECRUITING

Sanmenxia, China
Second People's Hospital Xiayi Country
RECRUITING

Shangqiu, China
Shandong Public Health Clinical Center
RECRUITING

Jinan, China
Shangcai County People's Hospital
RECRUITING

Zhumadian, China
Shangqiu Fourth People's Hospital
RECRUITING

Shangqiu, China
Shangqiu Hospital of Traditional Chinese Medicine
RECRUITING

Shangqiu, China
Shangqiu Municipal Hospital
RECRUITING

Shangqiu, China
Shangqiu Third People's Hospital
RECRUITING

Shangqiu, China
Shenqiu People's Hospital
RECRUITING

Zhoukou, China
Sheqi County People's Hospital
RECRUITING

Nanyang, China
Sui County People's Hospital
RECRUITING

Shangqiu, China
Suixian County Hospital of Traditional Chinese Medicine
RECRUITING

Shangqiu, China
Taikang County People's Hospital
RECRUITING

Zhoukou, China
Tanghe County People's Hospital
RECRUITING

Nanyang, China
Tangyin County People's Hospital
RECRUITING

Anyang, China
The 990th Hospital of the Joint Logistics Support Force of the PLA
RECRUITING

Zhumadian, China
The Fifth People's Hospital of Anyang
RECRUITING

Anyang, China
The Fifth People's Hospital of Puyang City
RECRUITING

Pujiang, China
The First Affiliated Hospital of Henan University of Chinese Medicine
RECRUITING

Zhengzhou, China
The First Affiliated Hospital of Henan University of Science and Technology
RECRUITING

Luoyang, China
The First Affiliated Hospital of Jinan University (Guangzhou Overseas Chinese Hospital)
RECRUITING

Guangzhou, China
The First Affiliated Hospital of Nanyang Medical College
RECRUITING

Nanyang, China
The First Affiliated Hospital of Xinxiang Medical University
RECRUITING

Xinxiang, China
The First Affiliated Hospital of Xinxiang Medical University (Hua County Branch)
RECRUITING

Anyang, China
The First Affiliated Hospital of Zhengzhou University
RECRUITING

Zhengzhou, China
The First People's Hospit of Zhengzhou
RECRUITING

Zhengzhou, China
The First People's Hospital of Lingbao
RECRUITING

Sanmenxia, China
The First People's Hospital of Shangqiu
RECRUITING

Shangqiu, China
The Frist People's Hospital Of Xiangcheng
RECRUITING

Zhoukou, China
The People's Hospital Of Biyang Country
RECRUITING

Zhumadian, China
The People's Hospital Of Luyi
RECRUITING

Zhoukou, China
The People's Hospital of Weishi
RECRUITING

Kaifeng, China
The People's Hospital of Yucheng County
RECRUITING

Shangqiu, China
The Secend People's Hospital of Jiaozuo
RECRUITING

Jiaozuo, China
The Second Affiliated Hospital of Zhengzhou University
RECRUITING

Zhengzhou, China
The Six People's Hospit of Zhengzhou
RECRUITING

Zhengzhou, China
The Sixth People's Hospital of Lingbao
RECRUITING

Sanmenxia, China
The Third Affiliated Hospital of Xinxiang Medical University
RECRUITING

Xinxiang, China
The Third People's Hospit of Zhengzhou
RECRUITING

Zhengzhou, China
The Third People's Hospital of Jiaozuo
RECRUITING

Jiaozuo, China
Third Affiliated Hospital of Henan University of Traditional Chinese Medicine
RECRUITING

Zhengzhou, China
Tongxu County People's Hospital
RECRUITING

Kaifeng, China
Weishi County People's Hospital
RECRUITING

Kaifeng, China
Wenxian People's Hospital
RECRUITING

Jiayuguan, China
Xiangcheng County Traditional Chinese Medicine Hospital
RECRUITING

Xuchang, China
Xiangcheng People's Hospital
RECRUITING

Xuchang, China
Xiayi County People's Hospital
RECRUITING

Shangqiu, China
Xihua County Hospital of Traditional Chinese Medicine
RECRUITING

Zhoukou, China
Xihua County People's Hospital
RECRUITING

Zhoukou, China
Xin'an County People's Hospital
RECRUITING

Luoyang, China
Xincai County People's Hospital
RECRUITING

Zhumadian, China
Xincai Medical University
RECRUITING

Zhumadian, China
Xingyang People's Hospital
RECRUITING

Zhengzhou, China
Xinxiang First People's Hospital
RECRUITING

Xinxiang, China
Xinxiang Infectious Disease Hospital
RECRUITING

Xinxiang, China
Xinyang Central Hospital
RECRUITING

Xinyang, China
Xinyang Specialized Hospital for Infectious Diseases
RECRUITING

Xinyang, China
Xinye County People's Hospital
RECRUITING

Nanyang, China
Xiping County People's Hospital
RECRUITING

Zhumadian, China
Xiuwu People's Hospital
RECRUITING

Jiaozuo, China
Xixia County People's Hospital
RECRUITING

Nanyang, China
Xixian People's Hospital
RECRUITING

Xinyang, China
Xuchang Central Hospital
RECRUITING

Xuchang, China
Xuchang People's Hospital
RECRUITING

Xuchang, China
Yanjin County People's Hospital
RECRUITING

Xinxiang, China
Yanling County People's Hospital
RECRUITING

Xuchang, China
Yanling County Traditional Chinese Medicine Hospital
RECRUITING

Xuchang, China
Yantai Qishan Hospital
RECRUITING

Yantai, China
Ye County People's Hospital
RECRUITING

Pingdingshan, China
Yichuan County Hospital of Traditional Chinese Medicine
RECRUITING

Luoyang, China
Yimei Group General Hospital
RECRUITING

Sanmenxia, China
Yiyang County People's Hospital
RECRUITING

Luoyang, China
Yongcheng Central Hospital
RECRUITING

Shangqiu, China
Yucheng County People's Hospital
RECRUITING

Shangqiu, China
Yuzhou Central Hospital
RECRUITING

Xuchang, China
Yuzhou City People's Hospital
RECRUITING

Xuchang, China
Zhecheng People's Hospital
RECRUITING

Shangqiu, China
Zhecheng Traditional Chinese Medicine Hospital Co., Ltd.
RECRUITING

Shangqiu, China
Zhengyang County People's Hospital
RECRUITING

Zhumadian, China
Zhengzhou Central Hospital
RECRUITING

Zhengzhou, China
Zhengzhou Traditional Chinese Medicine Hospital
RECRUITING

Zhengzhou, China
Zhenping People's Hospital
RECRUITING

Nanyang, China
Zhongmu County Hospital of Traditional Chinese Medicine
RECRUITING

Zhengzhou, China
Zhongmu County People's Hospital
RECRUITING

Zhengzhou, China
Zhongshan Second People's Hospital
RECRUITING

Zhongshan, China
Zhoukou Central Hospital
RECRUITING

Zhoukou, China
Zhoukou Hospital Of TCM
RECRUITING

Zhoukou, China
Zhoukou Specialized Disease Hospital
RECRUITING

Zhoukou, China
Zhumadian Central Hospital
RECRUITING

Zhumadian, China
Zhumadian Traditional Chinese Medicine Hospital
RECRUITING

Zhumadian, China
Zibo Central Hospital
RECRUITING

Zibo, China
Zibo Infectious Diseases Hospital (Zibo Fourth People's Hospital)
RECRUITING

Zibo, China

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