Could BCG and MMR vaccines tame COPD inflammation?
NCT ID NCT06257212
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study tested whether giving live vaccines (BCG and MMR) to people with COPD can train their immune system to produce less harmful inflammation. Sixty adults with COPD received either the vaccines or a placebo. Researchers measured changes in immune cell activity over four months to see if the vaccines could reduce systemic inflammation.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- BCG vaccine (Danish strain 1331) and MMR vaccine
- What this could lead to
- If it works, this could point toward a new way to reduce harmful inflammation in COPD using existing vaccines.
- What could go wrong
- This is a small pilot study with only 60 participants, so results may not apply widely. The vaccines also carry risks like allergic reactions or fever.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Department of Internal Medicine, Section of Respiratory Medicine
Hellerup, Copenhagen, 2900, Denmark
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