Needle-Free drug delivery tested in healthy volunteers

NCT ID NCT06741657

Completed Knowledge-focused Sponsor: Biogen Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed Phase 1 study tested whether giving the drug litifilimab under the skin using an autoinjector or a wearable on-body injector works as well as using a traditional syringe. 404 healthy volunteers received the drug by one of the three devices. Researchers measured drug levels in the blood and checked for side effects and injection site pain. The goal was to see if these automatic devices could be a good alternative for patients who have trouble using syringes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: litifilimab (BIIB059)
What this could lead to: If successful, this could make it easier for patients to receive litifilimab at home using automatic injectors instead of syringes.
What could go wrong: This is an early-phase study in healthy people, not patients. It only checks how the drug moves through the body, not whether it works for any disease.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEALTHY VOLUNTEER

Contacts and locations

Locations

Austin Clinical Research Unit

Austin, Texas, 78744, United States
Las Vegas Clinical Research Unit

Las Vegas, Nevada, 89113, United States

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