Head-to-Head: which mood stabilizer works best for bipolar II?
NCT ID NCT06184581
First seen Nov 01, 2025 · Last updated Jun 23, 2026 · Updated 28 times
Summary
This study compares two common mood stabilizers—lithium and lamotrigine—in 200 adults with bipolar II disorder. Over six months, participants will track their daily mood using a smartphone app to see which drug provides better mood stability. The goal is to find out which treatment works best for managing this condition.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Psychiatric Center Copenhagen
RECRUITINGCopenhagen, Denmark
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
lithium carbonate and lamotrigine
What this could lead to
If successful, this could help doctors choose the better mood-stabilizing drug for people with bipolar II disorder.
What could go wrong
This is a mid-stage trial with only 200 participants, so results may not apply to everyone. Both drugs have known side effects like kidney or thyroid issues.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.