Head-to-Head: which mood stabilizer works best for bipolar II?

NCT ID NCT06184581

Recruiting now Disease control Sponsor: University Hospital Bispebjerg and Frederiksberg Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two common mood stabilizers—lithium and lamotrigine—in 200 adults with bipolar II disorder. Over six months, participants will track their daily mood using a smartphone app to see which drug provides better mood stability. The goal is to find out which treatment works best for managing this condition.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: lithium carbonate and lamotrigine
What this could lead to: If successful, this could help doctors choose the better mood-stabilizing drug for people with bipolar II disorder.
What could go wrong: This is a mid-stage trial with only 200 participants, so results may not apply to everyone. Both drugs have known side effects like kidney or thyroid issues.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for BIPOLAR II DISORDER are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

bipolar disorder bipolar II disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BIPOLAR II DISORDER

Contacts and locations

Locations

Psychiatric Center Copenhagen
RECRUITING

Copenhagen, Denmark

More trials for these conditions

Other studies related to the condition(s) this trial covers.