New light on colon polyps: can special imaging boost detection?

NCT ID NCT07127471

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two methods for finding precancerous colon polyps during colonoscopy. Both methods use water instead of air to inflate the colon and an AI system to spot polyps. One group also uses a special light filter called linked-color imaging. The goal is to see if the extra imaging helps find more of the tricky, flat polyps that can turn into cancer. About 1090 adults aged 40-80 will take part.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Linked-color imaging (LCI) and computer-aided detection (CADe) system
What this could lead to
If successful, this could improve detection of hard-to-see precancerous polyps during colonoscopy, potentially reducing colon cancer risk.
What could go wrong
This is a device comparison study, not a treatment trial. The improvement may be small or not clinically meaningful, and results may not apply to all colonoscopy settings.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Evergreen General Hospital

    RECRUITING

    Taoyuan, 320, Taiwan

  • King Chulalongkorn Memorial Hospital

    NOT_YET_RECRUITING

    Bangkok, 10330, Thailand

  • Ospedale Valduce

    NOT_YET_RECRUITING

    Como, 22100, Italy

  • University of Montreal Medical Center (CHUM)

    NOT_YET_RECRUITING

    Montreal, Quebec, H2X 0A9, Canada

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