Lab-Grown corneal implant offers hope for advanced keratoconus

NCT ID NCT04653922

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This early safety study tested a bioengineered corneal implant called LinkCor in 20 adults with advanced keratoconus, a condition that thins and bulges the cornea. The implant is placed inside the cornea to flatten it and improve vision, without needing human donor tissue. Researchers checked for rejection and measured changes in corneal shape and eyesight over six months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

LinkCor bioengineered corneal implant

What this could lead to

If successful, this implant could offer a less invasive treatment for advanced keratoconus that does not rely on scarce human donor corneas.

What could go wrong

This is a very early, small safety study with only 20 participants. The implant may fail to improve vision or could be rejected, requiring removal.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

keratoconus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • All India Institute of Medical Sciences, Dr. R. P. Centre for Ophthalmic Sciences, AIIMS,

    New Delhi, 110029, India

  • Farabi Eye Hospital, Tehran University of Medical Sciences

    Tehran, 13366, Iran