Lab-Grown corneal implant offers hope for advanced keratoconus

NCT ID NCT04653922

Completed Disease control Sponsor: LinkoCare Life Sciences AB Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This early safety study tested a bioengineered corneal implant called LinkCor in 20 adults with advanced keratoconus, a condition that thins and bulges the cornea. The implant is placed inside the cornea to flatten it and improve vision, without needing human donor tissue. Researchers checked for rejection and measured changes in corneal shape and eyesight over six months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: LinkCor bioengineered corneal implant
What this could lead to: If successful, this implant could offer a less invasive treatment for advanced keratoconus that does not rely on scarce human donor corneas.
What could go wrong: This is a very early, small safety study with only 20 participants. The implant may fail to improve vision or could be rejected, requiring removal.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

keratoconus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

KERATOCONUS

Contacts and locations

Locations

All India Institute of Medical Sciences, Dr. R. P. Centre for Ophthalmic Sciences, AIIMS,

New Delhi, 110029, India
Farabi Eye Hospital, Tehran University of Medical Sciences

Tehran, 13366, Iran

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