Could a cooling sleeve protect nerves during chemo?
NCT ID NCT05095051
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a device that cools and compresses the arms and legs to see if it can prevent nerve damage caused by chemotherapy. The device is first tested in healthy volunteers to find the best temperature and pressure, then in cancer patients receiving weekly paclitaxel. The goal is to see if the treatment is safe and tolerable.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Paxman Cryocompression System (PCCS) - a device that cools and compresses the limbs
What this could lead to
If it works, this could offer a simple, non-drug way to prevent painful nerve damage caused by chemotherapy.
What could go wrong
This is a very early, small safety study. The device may be uncomfortable or cause side effects, and it is not yet proven to prevent nerve damage.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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National University Hospital
Singapore, 119074, Singapore