Light therapy may boost IVF success for older women

NCT ID NCT07425080

Recruiting now Disease control Sponsor: Columbia University Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether shining a special red light on eggs and embryos during IVF can help them develop better. As women age, their egg cells have less energy, which can make fertilization and embryo growth harder. The light treatment, called photobiomodulation, aims to boost the cells' energy production. Researchers will enroll 270 women using their own eggs and compare how many usable embryos develop with and without the light treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: photobiomodulation (low-level red light therapy)
What this could lead to: If it works, this could offer a simple, non-invasive way to improve IVF success rates, especially for older women.
What could go wrong: This is an early-stage dose-finding study, so the best light dose is unknown. The treatment may not improve embryo development or pregnancy rates.

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Conditions

The condition(s) this trial relates to.

infertility disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

IVF OUTCOMES

Contacts and locations

Locations

Columbia University Fertility Center
RECRUITING

New York, New York, 10019, United States

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