Moving with purpose: new study tests diet and exercise for MPN patients

NCT ID NCT05842603

Recruiting now Symptom relief Sponsor: Massachusetts General Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This pilot study tests whether a 12-week nutrition and exercise program is feasible for patients with myeloproliferative neoplasms (MPNs), a group of blood cancers. Thirty participants will take virtual and in-person classes to learn healthier eating and physical activity habits. The main goal is to see if at least 70% can complete 9 weeks of the program, with symptom changes also tracked.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Cardiac Lifestyle Program (12-week tailored nutrition and physical activity program)
What this could lead to: If successful, this could show that a structured lifestyle program is feasible for MPN patients and may help ease symptoms like fatigue.
What could go wrong: This is a very small pilot study (30 participants) with no control group, so results may not apply broadly. The program may be too demanding for some patients.

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Conditions

The condition(s) this trial relates to.

acquired polycythemia vera cellular phase chronic idiopathic myelofibrosis essential thrombocythemia leukemia myelofibrosis Myeloproliferative Disorders myeloproliferative neoplasm myeloproliferative neoplasm, unclassifiable

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LEUKEMIA MYELOPROLIFERATIVE DISORDERS

Contacts and locations

Locations

Brigham and Women's Hospital
RECRUITING

Boston, Massachusetts, 02215, United States
Dana-Farber Cancer Institute
NOT_YET_RECRUITING

Boston, Massachusetts, 02215, United States
Massachusetts General Hospital Cancer Center
RECRUITING

Boston, Massachusetts, 02215, United States

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