Could a simple puff of lidocaine protect Kids' brains during suctioning?

NCT ID NCT05058677

Completed Symptom relief Sponsor: The University of Texas Health Science Center, Houston Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Aug 07, 2026 · Updated 2 times

Summary

This study tested whether giving lidocaine as a mist before suctioning the breathing tube can prevent dangerous spikes in brain pressure in children with severe traumatic brain injury. Ten children in the pediatric ICU received either nebulized lidocaine, lidocaine dripped into the tube, or salt water. The goal was to see which method best keeps brain pressure stable during this routine but risky procedure.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: aerosolized lidocaine (nebulized lidocaine)
What this could lead to: If it works, this could offer a safer way to manage airway suctioning in children with severe brain injury, potentially reducing brain pressure spikes.
What could go wrong: This is a very small, early-phase trial with only 10 participants, so results may not apply broadly. The treatment is for temporary symptom control, not a cure.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Brain Injuries, Traumatic brain injury traumatic brain injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

TRAUMATIC BRAIN INJURY

Contacts and locations

Locations

The University of Texas Health Science Center at Houston

Houston, Texas, 77030, United States

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