Could a simple puff of lidocaine protect Kids' brains during suctioning?
NCT ID NCT05058677
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether giving lidocaine as a mist before suctioning the breathing tube can prevent dangerous spikes in brain pressure in children with severe traumatic brain injury. Ten children in the pediatric ICU received either nebulized lidocaine, lidocaine dripped into the tube, or salt water. The goal was to see which method best keeps brain pressure stable during this routine but risky procedure.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
aerosolized lidocaine (nebulized lidocaine)
What this could lead to
If it works, this could offer a safer way to manage airway suctioning in children with severe brain injury, potentially reducing brain pressure spikes.
What could go wrong
This is a very small, early-phase trial with only 10 participants, so results may not apply broadly. The treatment is for temporary symptom control, not a cure.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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The University of Texas Health Science Center at Houston
Houston, Texas, 77030, United States