Magnetic pulses to the brain may ease depression and sleep troubles
NCT ID NCT07638202
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This trial investigates whether adding low-intensity transcranial magnetic stimulation (Li-TMS) to standard antidepressant medication can improve depressive symptoms and sleep disorders in people with major depression. The study involves 40 participants who receive either real Li-TMS or a sham procedure, with both groups continuing their usual medication. Researchers also measure inflammation levels and brain-derived neurotrophic factor to explore how the treatment might work.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- low-intensity transcranial magnetic stimulation (Li-TMS)
- What this could lead to
- If it works, this could point toward a non-invasive add-on treatment for depression that also improves sleep and lowers inflammation.
- What could go wrong
- This is a small, early-stage trial with only 40 participants, so results may not apply widely. The treatment is experimental and may not outperform standard care.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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1Clinical Epidemiology Research Unit. OOAD Guanajuato. Mexican Social Security Institute, Leon, Mexico,
León, Guanajuato, 37328, Mexico
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