Magnetic pulses to the brain may ease depression and sleep troubles

NCT ID NCT07638202

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This trial investigates whether adding low-intensity transcranial magnetic stimulation (Li-TMS) to standard antidepressant medication can improve depressive symptoms and sleep disorders in people with major depression. The study involves 40 participants who receive either real Li-TMS or a sham procedure, with both groups continuing their usual medication. Researchers also measure inflammation levels and brain-derived neurotrophic factor to explore how the treatment might work.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

low-intensity transcranial magnetic stimulation (Li-TMS)

What this could lead to

If it works, this could point toward a non-invasive add-on treatment for depression that also improves sleep and lowers inflammation.

What could go wrong

This is a small, early-stage trial with only 40 participants, so results may not apply widely. The treatment is experimental and may not outperform standard care.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

major depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • 1Clinical Epidemiology Research Unit. OOAD Guanajuato. Mexican Social Security Institute, Leon, Mexico,

    León, Guanajuato, 37328, Mexico