New Two-Drug attack on aggressive leukemias that resist standard care

NCT ID NCT07356154

Summary

This early-stage study is testing whether combining two oral drugs, revumenib and mezigdomide, is safe and effective for people with specific types of acute leukemia that have returned or not responded to prior treatments. The trial will enroll about 52 participants aged 12 and older who have one of three specific genetic changes in their leukemia cells. The main goal of the first phase is to find the highest safe dose of the drug combination.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • City of Hope Cancer Center (Data collection only)

    NOT_YET_RECRUITING

    Duarte, California, 91010, United States

    Contact Phone: •••-•••-••••

  • MD Anderson Cancer Center (Data Collection Only)

    NOT_YET_RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Bergen (All Protocol Activities)

    RECRUITING

    Montvale, New Jersey, 07645, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Cancer Center (All Protocol Activities)

    RECRUITING

    New York, New York, 10065, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Monmouth (All Protocol Activities)

    RECRUITING

    Middletown, New Jersey, 07748, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Nassau (All Protocol Activities)

    RECRUITING

    Rockville Centre, New York, 11553, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Suffolk-Commack (All Protocol Activities)

    RECRUITING

    Commack, New York, 11725, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Westchester (Limited Protocol Activities)

    RECRUITING

    Harrison, New York, 10604, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering at Basking Ridge (All Protocol Activities)

    RECRUITING

    Basking Ridge, New Jersey, 07920, United States

    Contact Phone: •••-•••-••••

  • University of North Carolina (Data Collection Only)

    NOT_YET_RECRUITING

    Chapel Hill, North Carolina, 27514, United States

    Contact Phone: •••-•••-••••

Conditions

Explore the condition pages connected to this study.