New drug combo shows promise against rare skin cancer

NCT ID NCT04869137

First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 26 times

Summary

This study tested a combination of two drugs, lenvatinib and pembrolizumab, given before surgery to people with Merkel cell carcinoma, a rare and aggressive skin cancer. The goal was to see if the drugs could shrink or eliminate the tumor before it was removed. The trial enrolled 26 adults with stage II, III, or IV cancer. The main measure of success was whether no cancer cells remained in the removed tissue.

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Contacts and locations

Locations

  • Moffitt Cancer Center

    Tampa, Florida, 33612, United States

Conditions

Explore the condition pages connected to this study.