Blood test could predict chemo success in rare cancer

NCT ID NCT05653388

First seen Jan 04, 2026 · Last updated May 16, 2026 · Updated 21 times

Summary

This study looks at 200 people with metastatic leiomyosarcoma who are starting chemotherapy. Researchers collect blood samples before and during treatment to measure circulating tumor DNA (ctDNA) and see if changes in ctDNA can predict tumor shrinkage or longer survival. The goal is to find early markers that help doctors decide if chemotherapy is working, without giving any new treatment.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Chris O'Brien Lifehouse

    RECRUITING

    Camperdown, New South Wales, 2050, Australia

    Contact Email: •••••@•••••

  • Dana- Farber

    RECRUITING

    Boston, Massachusetts, 02215, United States

    Contact

  • MD Anderson

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Mayo Clinic

    RECRUITING

    Rochester, Minnesota, 55901, United States

    Contact

  • Memorial Sloan Kettering Cancer Center

    RECRUITING

    New York, New York, 10065, United States

    Contact

  • Ohio State University

    RECRUITING

    Columbus, Ohio, 43210, United States

    Contact

  • Peter MacCallum Cancer Centre

    RECRUITING

    Melbourne, Victoria, 3000, Australia

    Contact Email: •••••@•••••

  • Sarcoma Oncology Research Center

    RECRUITING

    Santa Monica, California, 90403, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of Miami

    RECRUITING

    Miami, Florida, 33136, United States

    Contact

    Contact

  • University of Michigan Cancer Center

    RECRUITING

    Ann Arbor, Michigan, 48109, United States

    Contact

    Contact Phone: •••-•••-••••

  • Vanderbilt University Medical Center

    RECRUITING

    Nashville, Tennessee, 37232, United States

    Contact Phone: •••-•••-••••

Conditions

Explore the condition pages connected to this study.