New knee implant aims for 10-Year durability in arthritis patients
NCT ID NCT07199738
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study is testing the LEGION Medial Stabilized knee implant in 144 people who need total knee replacement due to arthritis or joint damage. The goal is to see how well the implant holds up over 10 years without needing revision surgery. Participants will receive one of three versions of the implant, and their progress will be tracked for up to a decade.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
LEGION Medial Stabilized knee implant (device)
What this could lead to
If successful, this could confirm that the LEGION knee implant is safe and durable for long-term use, helping people with arthritis or joint damage get back to daily activities.
What could go wrong
This is a mid-stage study with only 144 participants, so results may not apply to everyone. There is always a risk of implant failure, infection, or need for revision surgery.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Medical University of South Carolina
Charleston, South Carolina, 29425, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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New York University Hospital
New York, New York, 10016, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Newton Wellesley Hospital
Newton, Massachusetts, 02462, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Rothman Orthopedics-Advent Health
Orlando, Florida, 32803, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The Core Institute
Phoenix, Arizona, 85023, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Wisconsin
Madison, Wisconsin, 53715-1218, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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