New drug trial aims to stop genetic Alzheimer's before it starts

NCT ID NCT06384573

Summary

This study is testing the drug lecanemab in people who have a genetic form of Alzheimer's disease and have already been in a related long-term trial. The main goal is to see if aggressively removing amyloid plaque from the brain years before symptoms typically appear can significantly delay or even prevent the onset of dementia. Researchers will closely monitor 40 participants to understand the long-term effects of this treatment approach.

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Contacts and locations

Locations

  • Indiana University School of Medicine

    Indianapolis, Indiana, 46202, United States

  • Neuroscience Research Australia

    Randwick, New South Wales, 2031, Australia

  • The National Hospital for Neurology and Neurosurgery

    London, Greater London, WC1B 3BG, United Kingdom

  • University of Alabama in Birmingham

    Birmingham, Alabama, 35294, United States

  • University of Washington

    Seattle, Washington, 98195, United States

  • Washington University in St. Louis

    St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.