Could a single pill replace two? new combo drug tested in healthy volunteers

NCT ID NCT07316608

Completed Knowledge-focused Sponsor: AstraZeneca Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed Phase 1 study tested whether a single tablet combining laroprovstat and rosuvastatin works as well as taking the two drugs separately. 44 healthy adults aged 18 to 55 took part in a crossover design, receiving different formulations. The goal was to measure how much of each drug gets into the blood, not to treat any condition.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Laroprovstat and rosuvastatin combined in a single tablet
What this could lead to: If successful, this could lead to a simpler, single-pill option for people who need both laroprovstat and rosuvastatin, making it easier to take their medications.
What could go wrong: This is an early-stage trial in healthy volunteers, not patients. It only measures how the body processes the drugs, not whether they work for any disease. The combined tablet may not work as well as separate pills.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Dyslipidemias hyperlipidemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEALTHY PARTICIPANTS

Contacts and locations

Locations

Research Site

Glendale, California, 91206, United States
Research Site

Brooklyn, Maryland, 21225, United States

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