Keyhole vs open surgery for colon cancer: which is better?

NCT ID NCT05713903

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study compares laparoscopic (keyhole) surgery to open surgery for removing the right side of the colon in people with right colon cancer. Both methods follow a precise technique called complete mesocolic excision (CME) to ensure thorough removal. The trial will enroll 114 adults aged 18-90 and measure how well each surgery removes the cancer, as well as recovery and complications.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Laparoscopic right colectomy or open right colectomy, both following complete mesocolic excision (CME) principles

What this could lead to

If successful, this could show that laparoscopic surgery is as effective as open surgery for removing right colon cancer, potentially leading to less invasive treatment.

What could go wrong

This is a relatively small trial (114 participants) and results may not apply to all patients. The study focuses on surgical technique quality, not long-term survival, so benefits may be limited.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

ascending colon cancer colon carcinoma colonic neoplasm neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Department of Surgery, University Hospital of Larissa

    RECRUITING

    Larissa, 41110, Greece

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact