Placenta extract shows promise for liver disease in early trial

NCT ID NCT05532124

Completed Disease control Sponsor: Green Cross Wellbeing Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed Phase 2 trial tested LAENNEC, a substance made from human placenta, in 49 adults with chronic liver disease. The study aimed to check if the treatment is safe and whether it can improve liver function, measured by a drop in ALT levels. Participants received either LAENNEC or a placebo through an IV, and researchers compared side effects and ALT changes between the groups.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: LAENNEC (human placenta hydrolysate)
What this could lead to: If successful, this could point toward a new treatment option to improve liver health in people with chronic liver disease.
What could go wrong: This is a small, early-phase trial (Phase 2) with only 49 participants. The results may not apply to everyone, and the treatment may not prove effective in larger studies.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

liver disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHRONIC LIVER DISEASE

Contacts and locations

Locations

Hanyang University Hospital.

Seoul, South Korea
Keimyung university dongsan medical center

Daegu, South Korea
Korea university guro hospital

Seoul, South Korea
Severance hospital

Seoul, South Korea
Soonchunhyang university hospital

Seoul, South Korea
Wonju severance christian hospital

Wŏnju, South Korea
Yeungnam university

Daegu, South Korea

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