Experimental cancer drug KZR-261 tested in phase 1 trial

NCT ID NCT05047536

First seen Jan 03, 2026 · Last updated May 16, 2026 · Updated 24 times

Summary

This early-stage study tested a new drug called KZR-261 in 61 people with advanced solid tumors that had stopped responding to standard treatments. The main goals were to check safety, find the right dose, and see if the drug could shrink tumors. The trial was terminated early, so results are limited.

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Contacts and locations

Locations

  • Cedars Sinai Medical Center

    Los Angeles, California, 90048, United States

  • Cleveland Clinic

    Cleveland, Ohio, 44195, United States

  • Fox Chase Cancer Center

    Philadelphia, Pennsylvania, 19111, United States

  • Fred Hutchinson Cancer Center

    Seattle, Washington, 98109, United States

  • Henry Ford Health System

    Detroit, Michigan, 48202, United States

  • Moffitt Cancer Center

    Tampa, Florida, 33612, United States

  • START (South Texas Accelerated Research Therapeutics)

    San Antonio, Texas, 78229, United States

  • Sara Cannon Research Institution (SCRI) - Tennessee Oncology Nashville

    Nashville, Tennessee, 37203, United States

  • University Hospitals - Cleveland Medical Center

    Cleveland, Ohio, 44106, United States

  • University of California Los Angeles

    Los Angeles, California, 90095, United States

  • Virginia Cancer Specialists (VCS)

    Fairfax, Virginia, 22031, United States

  • Winship Cancer Institute of Emory University

    Atlanta, Georgia, 30322, United States

Conditions

Explore the condition pages connected to this study.