Stem cell injection could ease knee arthritis pain without surgery

NCT ID NCT05027581

Completed Disease control Sponsor: Taiwan Bio Therapeutics Inc. Source: ClinicalTrials.gov ↗

First seen Jul 06, 2026 · Last updated Jul 07, 2026 · Updated 1 time

Summary

This trial tests whether a single injection of stem cells, called Chondrochymal®, can reduce pain and improve function in people with knee osteoarthritis. Participants are adults aged 40 to 80 with moderate to severe knee arthritis who are not ready for or cannot have knee surgery. The study compares the stem cell treatment to an active control to see if it safely eases symptoms.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Chondrochymal® (bone marrow mesenchymal stem cells)
What this could lead to: If it works, this could lead to a non-surgical treatment that reduces knee pain and improves function in people with knee osteoarthritis.
What could go wrong: This is an early-phase trial with only 72 participants, so results may not apply to everyone. Stem cell treatments can have side effects like infection or immune reactions.

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Conditions

The condition(s) this trial relates to.

osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OSTEOARTHRITIS, KNEE

Contacts and locations

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Locations

Taipei Municipal Wangfang Hospital (Managed by Taipei Medical University)

Taipei, Wenshan District, 116, Taiwan
Taipei Veterans General Hospital

Taipei, Beitou District, 112, Taiwan

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