New CAR T-Cell therapy KITE-753 takes on axi-cel in lymphoma showdown

NCT ID NCT07479797

First seen Mar 26, 2026 · Last updated Apr 25, 2026 · Updated 4 times

Summary

This study tests a new treatment called KITE-753 against an approved CAR T-cell therapy (axi-cel) in adults with large B-cell lymphoma that came back or didn't respond after initial treatment. About 550 participants will be randomly assigned to receive one of the two therapies. The main goal is to see which treatment leads to more complete remissions at 6 months and longer event-free survival.

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