New drug combo shows promise for hard-to-treat lymphoma
NCT ID NCT05852717
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a combination of the immunotherapy drug epcoritamab with standard chemotherapy (GDP) in 32 adults whose large B-cell lymphoma has returned or not responded to treatment. The goal is to see if the combo can shrink tumors enough to allow for a stem cell transplant or CAR T-cell therapy. Participants receive three 21-day cycles of the combo, then may continue with epcoritamab alone if they respond but cannot proceed to transplant.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Indiana University Melvin and Bren Simon Comprehensive Cancer Center
RECRUITINGIndianapolis, Indiana, 46202, United States
Contact Email: •••••@•••••
Contact
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Karmanos Cancer Center (Wayne State University)
RECRUITINGDetroit, Michigan, 48201, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Texas Southwestern Medical Center
RECRUITINGDallas, Texas, 75390, United States
Contact
Contact Email: •••••@•••••
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University of Virginia Health System
RECRUITINGCharlottesville, Virginia, 22908, United States
Contact
Contact Email: •••••@•••••