One shot to shield kidneys from surgery damage?

NCT ID NCT05746559

Ongoing Disease control Sponsor: Alexion Pharmaceuticals, Inc. Source: ClinicalTrials.gov ↗

Summary

This study is testing whether a single dose of the drug ravulizumab can protect the kidneys of people with chronic kidney disease who are having planned heart surgery. The goal is to prevent serious kidney injury and related complications that can occur after surgery. About 736 participants will receive either the drug or a placebo before their operation to see if it reduces kidney problems in the 90 days following surgery.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Show contact details

Locations

Research Site

Tucson, Arizona, 85719, United States
Research Site

Orange, California, 92868, United States
Research Site

San Francisco, California, 94121, United States
Research Site

San Francisco, California, 94143, United States
Research Site

Stanford, California, 94305, United States
Research Site

Aurora, Colorado, 80045, United States
Research Site

Weston, Florida, 33331, United States
Research Site

Atlanta, Georgia, 30309, United States
Research Site

Chicago, Illinois, 60637, United States
Research Site

Indianapolis, Indiana, 46237, United States
Research Site

Boston, Massachusetts, 02115, United States
Research Site

Springfield, Massachusetts, 01107, United States
Research Site

Detroit, Michigan, 48201, United States
Research Site

Kansas City, Missouri, 64111, United States
Research Site

St Louis, Missouri, 63110, United States
Research Site

Rochester, New York, 14621, United States
Research Site

Valhalla, New York, 10595, United States
Research Site

Winston-Salem, North Carolina, 27157, United States
Research Site

Fargo, North Dakota, 58102, United States
Research Site

Cleveland, Ohio, 44126, United States
Research Site

Columbus, Ohio, 43210, United States
Research Site

Philadelphia, Pennsylvania, 19140, United States
Research Site

Charleston, South Carolina, 29425, United States
Research Site

Dallas, Texas, 75390, United States
Research Site

San Antonio, Texas, 78229, United States
Research Site

Salt Lake City, Utah, 84132, United States
Research Site

Charlottesville, Virginia, 22908, United States
Research Site

Richmond, Virginia, 23298, United States
Research Site

Seattle, Washington, 98195, United States
Research Site

Buenos Aires, C1180AAV, Argentina
Research Site

Ciudad de Buenos Aires, C1199ABB, Argentina
Research Site

Ciudad de Buenos Aires, C1428, Argentina
Research Site

Corrientes, W3400AMZ, Argentina
Research Site

Santa Fe, S3000EOM, Argentina
Research Site

Adelaide, 5000, Australia
Research Site

Brisbane, 4102, Australia
Research Site

Monash, Australia
Research Site

Murdoch, 6150, Australia
Research Site

Southport, 4215, Australia
Research Site

Vienna, A-1090, Austria
Research Site

Belo Horizonte, 30150-221, Brazil
Research Site

Brasília, 70658-700, Brazil
Research Site

Fortaleza, 60430-375, Brazil
Research Site

Recife, 50070-550, Brazil
Research Site

Ribeirão Preto, 14051-140, Brazil
Research Site

Rio de Janeiro, 22270-005, Brazil
Research Site

Salvador, 40301-155, Brazil
Research Site

São José do Rio Preto, 15090-000, Brazil
Research Site

São Paulo, 01323-900, Brazil
Research Site

São Paulo, 04012-180, Brazil
Research Site

São Paulo, 05403-000, Brazil
Research Site

Edmonton, Alberta, T6G 2B7, Canada
Research Site

Winnipeg, Manitoba, R2H 2A6, Canada
Research Site

Saint John, New Brunswick, E2L 4L4, Canada
Research Site

Hamilton, Ontario, L8L 2X2, Canada
Research Site

Kingston, Ontario, K7L 2V7, Canada
Research Site

Toronto, Ontario, M5B 1W8, Canada
Research Site

Montreal, Quebec, H1T 1C8, Canada
Research Site

Montreal, Quebec, H2X 0C1, Canada
Research Site

Montreal, Quebec, H4J 1C5, Canada
Research Site

Beijing, 100029, China
Research Site

Huai'an, 223300, China
Research Site

Shanghai, 200032, China
Research Site

Shanghai, 200080, China
Research Site

Shenzhen, 518036, China
Research Site

Shenzhen, 518053, China
Research Site

Tianjin, 300050, China
Research Site

Wuhan, CN-430022, China
Research Site

Xi'an, 710061, China
Research Site

Zhengzhou, 450000, China
Research Site

Zhengzhou, 450002, China
Research Site

Zhengzhou, 450007, China
Research Site

Zhengzhou, 450052, China
Research Site

Bordeaux, 33074, France
Research Site

Dijon, 21079, France
Research Site

Montpellier, 34000, France
Research Site

Toulouse, 31076, France
Research Site

Essen, 45147, Germany
Research Site

Frankfurt am Main, 60590, Germany
Research Site

Giessen, 35392, Germany
Research Site

Halle, 06120, Germany
Research Site

Heidelberg, 69120, Germany
Research Site

Jena, 07747, Germany
Research Site

München, 81377, Germany
Research Site

Stuttgart, 70376, Germany
Research Site

Trier, 54292, Germany
Research Site

Hong Kong, 999077, Hong Kong
Research Site

Bangalore, 560069, India
Research Site

Bangalore, 560092, India
Research Site

Delhi, 110025, India
Research Site

Delhi, 110060, India
Research Site

Gūrgaon, 122001, India
Research Site

Hyderabad, 500 034, India
Research Site

Mysuru, 570004, India
Research Site

Secunderabad, 500003, India
Research Site

Haifa, 3109601, Israel
Research Site

Haifa, 34362, Israel
Research Site

Bari, 70124, Italy
Research Site

Florence, 50134, Italy
Research Site

Milan, 20138, Italy
Research Site

Naples, 80131, Italy
Research Site

Bunkyō City, 113-8431, Japan
Research Site

Chūōku, 104-8560, Japan
Research Site

Kamakura-shi, 247-8533, Japan
Research Site

Kawasaki-shi, 216-8511, Japan
Research Site

Minatoku, 105-8470, Japan
Research Site

Okayama, 700-0804, Japan
Research Site

Sagamihara-shi, 252-0375, Japan
Research Site

Suginami City, 168-0065, Japan
Research Site

Urayasu, 279-0001, Japan
Research Site

Groningen, 9713 GZ, Netherlands
Research Site

Maastricht, 6229 HX, Netherlands
Research Site

Bialystok, 15-276, Poland
Research Site

Bielsko-Biala, 43-316, Poland
Research Site

Chrzanów, 32-500, Poland
Research Site

Katowice, 40-635, Poland
Research Site

Krakow, 31-202, Poland
Research Site

Lodz, 91-347, Poland
Research Site

Lodz, 92-213, Poland
Research Site

Poznan, 60-355, Poland
Research Site

Szczecin, 70-111, Poland
Research Site

Tychy, 43-100, Poland
Research Site

Warsaw, 02-972, Poland
Research Site

Anyang-si, 14068, South Korea
Research Site

Bucheon-si, 14754, South Korea
Research Site

Busan, 49241, South Korea
Research Site

Daegu, 42601, South Korea
Research Site

Seongnam-si, 13620, South Korea
Research Site

Seoul, 02841, South Korea
Research Site

Seoul, 03080, South Korea
Research Site

Seoul, 06351, South Korea
Research Site

Seoul, 08308, South Korea
Research Site

Seoul, 120-752, South Korea
Research Site

A Coruña, 15006, Spain
Research Site

Barcelona, 08036, Spain
Research Site

Barcelona, 8035, Spain
Research Site

Córdoba, 14004, Spain
Research Site

Madrid, 28040, Spain
Research Site

Madrid, 28041, Spain
Research Site

Majadahonda, 28250, Spain
Research Site

Navarra, 31190, Spain
Research Site

Seville, 41071, Spain
Research Site

Valencia, 46010, Spain
Research Site

Valladolid, 47003, Spain
Research Site

Hualien City, 970473, Taiwan
Research Site

Kaohsiung City, 83301, Taiwan
Research Site

New Taipei City, 220, Taiwan
Research Site

Taichung, 40447, Taiwan
Research Site

Tainan, 70403, Taiwan
Research Site

Taipei, 10002, Taiwan
Research Site

Taipei, 11696, Taiwan
Research Site

Ankara, 06800, Turkey (Türkiye)
Research Site

Antalya, 07100, Turkey (Türkiye)
Research Site

Istanbul, 34303, Turkey (Türkiye)
Research Site

Istanbul, 34846, Turkey (Türkiye)
Research Site

Menemen/Izmir, 35665, Turkey (Türkiye)
Research Site

Odunpazari, 26080, Turkey (Türkiye)
Research Site

Cambridge, CB2 0AY, United Kingdom
Research Site

Clydebank, G81 4DY, United Kingdom
Research Site

Edinburgh, EH16 4SA, United Kingdom
Research Site

London, SE1 9RT, United Kingdom
Research Site

London, SW17 0QT, United Kingdom
Research Site

London, W12 0HS, United Kingdom
Research Site

Newcastle upon Tyne, NE7 7DN, United Kingdom

Conditions

Explore the condition pages connected to this study.

CARDIAC DISEASE CARDIOPULMONARY BYPASS CHRONIC KIDNEY DISEASE CKD