Global trial aims to shield fragile kidneys from deadly heart attacks

NCT ID NCT03969953

Summary

This large, late-stage trial is testing whether a low dose of the blood-thinning drug rivaroxaban can safely reduce the risk of heart attacks, strokes, and death in people with advanced or dialysis-dependent kidney disease. It will enroll 2,000 participants worldwide who have kidney disease and are at high risk for heart problems. The study compares the drug against a placebo to see if it provides a net benefit by preventing major heart events without causing excessive bleeding.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • AIIMS Bhubaneswar

    Bhubaneswar, India

  • AURAL Colmar, (AURAL Colmar)

    Colmar, 68000, France

  • AURAL Haguenau, (AURAL Haguenau)

    Haguenau, 67500, France

  • AURAL Mulhouse, (AURAL Mulhouse)

    Mulhouse, 68100, France

  • AURAL Strasbourg, (AURAL Strasbourg)

    Strasbourg, 67000, France

  • AZ Sint-Jan Brugge

    Bruges, Belgium

  • All India Institute Of Medical Sciences, Raipur

    Raipur, Chhattisgarh, 700020, India

  • All India Institute of Medical Sciences, Bathinda

    Bathinda, Punjab, 151001, India

  • Apollo Hospital

    Chennai, Tamil Nadu, India

  • Asian Institute of Nephrology and Urology

    Hyderabad, India

  • Aykai Super Speciality Hospital, Ludhiana

    Ludhiana, Punjab, 141010, India

  • Aysha Hospital

    Chennai, Tamil Nadu, 600010, India

  • Bendigo Health

    Bendigo, Victoria, 3552, Australia

  • CH Boulogne-sur-Mer, (CH Boulogne-sur-Mer)

    Boulogne-sur-Mer, 62200, France

  • CH Haguenau, (CH Haguenau)

    Haguenau, 67500, France

  • CH Le Puy-en-Velay

    Le Puy-en-Velay, France

  • CH Mulhouse, (CH Mulhouse)

    Mulhouse, 68100, France

  • Canberra Hospital

    Garran, Australian Capital Territory, 2605, Australia

  • Centre Hospitalier Régional Universitaire de Nancy

    Nancy, Meurthe-et-Moselle, 54035, France

  • Chang Gung Memorial Hospital, Linkou Medical Center

    Taoyuan District, 333, Taiwan

  • Charles Nicolle Hospital

    Tunis, Tunisia

  • Chung-Shan Medical University Hospital

    Taichung, 402, Taiwan

  • Citizens Hospital

    Hyderabad, Telangana, 500019, India

  • Concord Repatriation General Hospital

    Concord, New South Wales, 2139, Australia

  • Dialysis Centre - King Abdul Aziz Medical City (KAMC)

    Ar Rimāyah, Riyadh Region, 11481, Saudi Arabia

  • Fattouma Bourguiba Hospital

    Monastir, Tunisia

  • Fu-Jen Catholic University Hospital

    Taishan, New Taipei City, 243, Taiwan

  • Government Hospital

    Nandyāl, 518501, India

  • Government Hospital

    Proddatūr, 516362, India

  • Hedi chaker Hospital

    Sfax, Tunisia

  • Hemodialysis Care Project North Centre

    Al Yāsamīn, Riyadh Region, 13322, Saudi Arabia

  • Hemodialysis Care Project South Centre

    Riyadh, Riyadh Region, 12799-6176, Saudi Arabia

  • Hemodialysis King Abdullah Centre

    Al Yāsamīn, Riyadh Region, 13322, Saudi Arabia

  • Hopital Louis Pasteur (CH Colmar)

    Colmar, France

  • Hospital Ampang

    Ampang, Malaysia

  • Hospital Canselor Tuanku Muhriz

    Kuala Lumpur, Kuala Lumpur, 56000, Malaysia

  • Hospital Kajang

    Kajang, Selangor, 43000, Malaysia

  • Hospital Pakar Sultanah Fatimah Muar

    Muar town, Malaysia

  • Hospital Queen Elizabeth, Kota Kinabalu

    Kota Kinabalu, Sabah, 88200, Malaysia

  • Hospital Raja Perempuan Zainab II

    Kota Bharu, Kelantan, 15586, Malaysia

  • Hospital Raja Permaisuri Bainun, Ipoh

    Ipoh, Perak, 30450, Malaysia

  • Hospital Seberang Jaya

    Seberang Jaya, Pulau Pinang, 13700, Malaysia

  • Hospital Sultanah Bahiyah

    Alor Star, Kedah, 05460, Malaysia

  • Hospital Tuanku Ja'afar, Seremban

    Seremban, Negeri Sembilan, 70300, Malaysia

  • Hôpital Bretonneau, (CHRU Tours)

    Tours, 37000, France

  • Hôpital Edouard Herriot, (CHU Lyon)

    Lyon, 69003, France

  • Hôpital Pasteur, (CHU Nice)

    Nice, 06000, France

  • Hôpital de la Cavale Blanche, (CHU Brest)

    Brest, 29200, France

  • Hôpital de la Conception, (AP-HM)

    Marseille, 13005, France

  • Hôpital de la Maison Blanche, (CHU Reims)

    Reims, 51092, France

  • Hôpitaux de Brbaois, (ALTIR)

    Vandœuvre-lès-Nancy, 54500, France

  • Institute of Post-Graduate Medical Education and Research

    Kolkata, 700020, India

  • KG Hospital, K.Govindaswamy Naidu Medical Trust

    Coimbatore, 641018, India

  • KRH Klinikum Siloah

    Hanover, Germany

  • Kaohsiung Chang-Gung Memorial Hospital

    Kaohsiung City, 833, Taiwan

  • Kaohsiung Medical University Chung-Ho Memorial Hospital

    Kaohsiung City, 807, Taiwan

  • Khoo Teck Puat Hospital

    Singapore, 767828, Singapore

  • King Abdulaziz Medical City - Western Region - Jeddah, Ministry of National Guard - Health Affairs

    Jeddah, Saudi Arabia

  • King Saud University Medical City (KSUMC)

    Riyadh, Saudi Arabia

  • La Rabta Hospital

    Tunis, Tunisia

  • Logan Hospital

    Meadowbrook, Queensland, 4131, Australia

  • Military Hospital

    Tunis, Tunisia

  • Mongi Slim Hospital

    Tunis, Tunisia

  • Muljibhai Patel Urological Hospital

    Nadiād, Gujarat, 387001, India

  • Nepean Hospital

    Kingswood, New South Wales, 2747, Australia

  • Nil Ratan Sircar Medical College and Hospital

    Kolkata, India

  • Nizam's Institute of Medical Sciences, Hyderabad

    Hyderabad, Telangana, 500082, India

  • Noble Annex Hospital

    Hadapsar, Pune Maharashtra, 411013, India

  • Nutema Hospital

    Meerut, Uttar Pradesh, India

  • Osmania General Hospital

    Hyderabad, Telangana, 500012, India

  • Postgraduate Institute of Medical Education and Research, Chandigarh

    Chandigarh, 160012, India

  • Prince of Wales Hospital

    Randwick, New South Wales, 2031, Australia

  • Research St. Joseph's - Hamilton

    Hamilton, Canada

  • Royal Adelaide Hospital

    Adelaide, South Australia, 5000, Australia

  • Royal North Shore Hospital

    St Leonards, New South Wales, 2065, Australia

  • Safdarjung Hospital

    New Delhi, India

  • Sahloul Hospital

    Sousse, Tunisia

  • St George Hospital

    Kogarah, New South Wales, 2217, Australia

  • Sunshine Hospital

    St Albans, Victoria, 3021, Australia

  • Taher Sfar Hospital

    Tunis, Tunisia

  • Taipei Tzu Chi Hospital

    Taipei, 231, Taiwan

  • Tan Tock Seng Hospital

    Singapore, 308433, Singapore

  • Tribhuvan University College

    Kathmandu, Nepal

  • University of Alberta

    Edmonton, Canada

  • University of Malaya Medical Centre

    Kuala Lumpur, Kuala Lumpur, 59100, Malaysia

  • VS Hospital

    Kilpauk, 600010, India

  • Wan fang Hospital

    Taipei, 116, Taiwan

  • Wollongong Hospital

    Wollongong, New South Wales, 2500, Australia

Conditions

Explore the condition pages connected to this study.