Can ketamine and brain scans help curb alcohol cravings?
NCT ID NCT06969937
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a single dose of ketamine, combined with real-time brain training (neurofeedback), can help people with alcohol use disorder drink less. 75 participants will receive either ketamine or placebo, plus real or fake neurofeedback. The goal is to see if the combination reduces heavy drinking days and changes brain chemistry related to cravings.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Ketamine
What this could lead to
If successful, this could point toward a new treatment that helps people with alcohol use disorder reduce their drinking by targeting brain chemistry and cravings.
What could go wrong
This is a small, early Phase 2 trial with only 75 participants, so results may not apply to everyone. Ketamine can cause side effects like dissociation or nausea, and the neurofeedback training requires multiple MRI sessions.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Psychiatric University Zurich, University of Zurich
RECRUITINGZurich, 8032, Switzerland