Ketamine challenged as safe option for severe brain injury in tiny new study
NCT ID NCT06062628
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This early-phase study is testing whether a single dose of ketamine is safe for people with severe traumatic brain injury. Researchers will measure changes in brain pressure and oxygen levels in 10 critically ill adults. The goal is to see if ketamine, which has sedative and pain-relieving properties, can be used without causing harm.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Ketamine
What this could lead to
If successful, this could show that ketamine is safe for severe TBI patients and may help guide better sedation practices.
What could go wrong
This is a very small, early-phase pilot study with only 10 participants, so results may not apply broadly. Ketamine has long been thought to raise brain pressure, and this risk is still being investigated.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Parkland Memorial Hospital
RECRUITINGDallas, Texas, 75235, United States
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Parkland Memorial Hospital
RECRUITINGDallas, Texas, 75235, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••