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New hope for myelofibrosis patients: experimental drug KER-050 enters phase 2 trial

NCT ID NCT05037760

Recruiting now Disease control Sponsor: Takeda Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new drug called elritercept (KER-050) for people with myelofibrosis, a rare bone marrow disorder. The drug is given alone or with the standard treatment ruxolitinib. The main goals are to check safety and see if it helps with anemia and other symptoms. About 135 adults will take part in this phase 2 trial.

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Conditions

The condition(s) this trial relates to.

anemia myelofibrosis primary myelofibrosis thrombocytopenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MYELOFIBROSIS

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

Locations

  • ASST Grande Ospedale Metropolitano Niguarda, Niguarda Cancer Center

    RECRUITING

    Milan, Italy

  • Albert Einstein Sociedade Beneficente Israelita Brasiliera

    RECRUITING

    São Paulo, Brazil

  • Arcispedale S. Maria Nuova Azienda Ospedaliera di Reggio Emilia

    RECRUITING

    Reggio Emilia, Italy

  • Azienda Ospedaliera Universitaria Careggi

    RECRUITING

    Florence, Italy

  • Azienda Ospedaliera Universitaria Integrata Verona

    RECRUITING

    Verona, Italy

  • Azienda Ospedaliera Universitaria Policlinico Sant'Orsola Malpighi

    RECRUITING

    Bologna, Italy

  • Azienda Ospedaliera Universitaria Policlinico Umberto I

    RECRUITING

    Roma, Italy

  • Azienda Ospedaliero Universitaria Consorziale Policlinico di Bari

    RECRUITING

    Bari, Italy

  • Azienda Socio Sanitaria Territoriale Sette Laghi

    RECRUITING

    Varese, Italy

  • Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia

    RECRUITING

    Brescia, Italy

  • Ballarat Oncology & Haematology Service

    RECRUITING

    Wendouree, Victoria, 3355, Australia

  • CHU Amiens - Hopital Sud

    COMPLETED

    Amiens, France

  • Centre Hospitalier Lyon Sud

    RECRUITING

    Lyon, France

  • Concord Hospital

    RECRUITING

    Concord, New South Wales, Australia

  • Flinders Medical Centre

    RECRUITING

    Woodville South, South Australia, 5042, Australia

  • Fondazione IRCCS CA' Granda Ospedale Maggiore Policlinico

    RECRUITING

    Milan, Italy

  • Fondazione Policlinico Universitario Agostino Gemelli IRCCS

    COMPLETED

    Milan, Italy

  • Gachon University Gil Medical Center

    COMPLETED

    Incheon, South Korea

  • Guys Hospital

    RECRUITING

    London, United Kingdom

  • Hammersmith Hospital

    RECRUITING

    London, United Kingdom

  • Hopital Morvan

    COMPLETED

    Brest, France

  • Hopital Prive Sevigne

    COMPLETED

    Cesson-Sévigné, France

  • Hopital de la Source - CHR Orleans

    COMPLETED

    Orléans, France

  • Hospital Beneficencia Portuguesa de Sao Paulo

    RECRUITING

    São Paulo, Brazil

  • Hospital Clinico Universitario de Valencia

    RECRUITING

    Valencia, Spain

  • Hospital Das Clinicas Da Faculdade de Medicina Da U S P

    RECRUITING

    São Paulo, Brazil

  • Hospital QuironSalud de Zaragoza

    RECRUITING

    Zaragoza, Spain

  • Hospital Universitari Vall d'Hebron

    RECRUITING

    Barcelona, Spain

  • Hospital Universitario La Paz

    RECRUITING

    Madrid, Spain

  • Hospital Universitario La Princesa

    RECRUITING

    Madrid, Spain

  • Hospital Universitario de Salamanca

    RECRUITING

    Salamanca, Spain

  • Hospital de Clinicas de Porto Alegre

    RECRUITING

    Porto Alegre, Brazil

  • ICO Badalona - Hospital Universitari Germans Trias i Pujol

    RECRUITING

    Badalona, Spain

  • IMV-Pesquisa Cardiologica Sociedade Simples

    RECRUITING

    Porto Alegre, Brazil

  • Institut de Cancerologie du Gard

    RECRUITING

    Nîmes, France

  • Instituto de Ensino e Pesquisas Sao Lucas

    RECRUITING

    São Paulo, Brazil

  • Ospedale Policlinico San Martino

    RECRUITING

    Genova, Italy

  • Royal Melbourne Hospital

    RECRUITING

    Melbourne, Victoria, 3050, Australia

  • Samsung Medical Center

    COMPLETED

    Seoul, South Korea

  • Seoul St. Marys Hospital, The Catholic University of Korea

    RECRUITING

    Seoul, South Korea

  • Soonchunhyang University Seoul Hospital

    RECRUITING

    Seoul, South Korea

  • St James Hospital,Leeds

    RECRUITING

    Leeds, United Kingdom

  • St. Vincents Hospital Melbourne

    RECRUITING

    Fitzroy, Victoria, 3355, Australia

  • The Tweed Hospital

    RECRUITING

    Tweed Heads, New South Wales, 2485, Australia

  • United Lincolnshire Hospitals NHS Trust - Pilgrim Hospital

    RECRUITING

    Boston, United Kingdom

  • University College London

    RECRUITING

    London, United Kingdom

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