New hope for schizophrenia: KarXT enters Late-Stage trial
NCT ID NCT06882785
First seen Jun 24, 2026 · Last updated Jul 01, 2026 · Updated 3 times
Summary
This phase 3 study tests whether KarXT, a new drug, can safely reduce schizophrenia symptoms in 250 Japanese adults experiencing acute psychosis. Participants first receive either KarXT or a placebo for 5 weeks, then all may receive KarXT for a year. The goal is to see if KarXT improves symptoms like hallucinations and disorganized thinking.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
KarXT (also known as BMS-986510)
What this could lead to
If successful, KarXT could offer a new treatment option for schizophrenia, helping to control symptoms like hallucinations and delusions.
What could go wrong
This is a phase 3 trial, but it is still early to know if KarXT works better than existing treatments. Side effects are possible, and results may not apply to all patients.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for SCHIZOPHRENIA are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
-
Contact
Locations
-
Asuka Hospital
RECRUITINGMachida, Tokyo, 1940005, Japan
Contact Phone: •••-•••-••••
-
Dokkyo Medical University Hospital
RECRUITINGShimotsuga, Tochigi, 321-0293, Japan
Contact Phone: •••-•••-••••
-
Fujimidai Hospital
RECRUITINGHiratsuka, Kanagawa, 259-1205, Japan
Contact Phone: •••-•••-••••
-
Fujita Health University
RECRUITINGToyoake, Aichi-ken, 470-1192, Japan
Contact Phone: •••-•••-••••
-
Goryokai Medical Corporation - Goryokai Hospital
RECRUITINGSapporo, Hokkaido, 002-8029, Japan
Contact Phone: •••-•••-••••
-
Hino Hospital - Yokohama
RECRUITINGYokohama, Kanagawa, 234-0051, Japan
Contact Phone: •••-•••-••••
-
Hokkaido University Hospital
RECRUITINGSapporo, Hokkaido, 0608648, Japan
Contact Phone: •••-•••-••••
-
Holy Cross Hospital - Toki
RECRUITINGToki, Gifu, 509-5142, Japan
Contact Phone: •••-•••-••••
-
Hotei Hospital
RECRUITINGKōnan, Aichi-ken, 4838248, Japan
Contact Phone: •••-•••-••••
-
Inuo Hospital
RECRUITINGTosu, Saga-ken, 841-0081, Japan
Contact Phone: •••-•••-••••
-
Kansai Medical University Medical Center
RECRUITINGMoriguchi, Osaka, 570-8507, Japan
Contact Phone: •••-•••-••••
-
Kitasato University Hospital
RECRUITINGSagamihara, Kanagawa, 252-0375, Japan
Contact Phone: •••-•••-••••
-
Kuramitsu Hospital
RECRUITINGFukuoka, 819-0037, Japan
Contact Phone: •••-•••-••••
-
Kure Medical Center
RECRUITINGKure, Hiroshima, 737-0023, Japan
Contact Phone: •••-•••-••••
-
Local Institution - 0012
WITHDRAWNHachiōji, Tokyo, 192-0153, Japan
-
Local Institution - 0014
WITHDRAWNKomoro, Nagano, 384-8540, Japan
-
Local Institution - 0018
NOT_YET_RECRUITINGOkinawa, 904-0012, Japan
Contact
-
Local Institution - 0019
WITHDRAWNYatsushiro, Kumamoto, 866-0043, Japan
-
Local Institution - 0025
NOT_YET_RECRUITINGHadano-shi, Kanagawa, 257-0003, Japan
Contact
-
Local Institution - 0031
NOT_YET_RECRUITINGOsaka, 590-0018, Japan
Contact
-
Local Institution - 0032
WITHDRAWNIizuka, Fukuoka, 820-0014, Japan
-
Local Institution - 0033
WITHDRAWNTottori, 689-0203, Japan
-
Local Institution - 0037
NOT_YET_RECRUITINGKitakyushu, Fukuoka, 803-0831, Japan
Contact
-
Local Institution - 0043
NOT_YET_RECRUITINGUtsunomiya, Tochigi, 3291104, Japan
Contact
-
Local Institution - 0050
WITHDRAWNMatsumoto, Nagano, 390-0847, Japan
-
Local Institution - 0054
NOT_YET_RECRUITINGShimotsuke, Tochigi, 329-0498, Japan
Contact
-
Local Institution - 0056
NOT_YET_RECRUITINGNagoya, Aichi-ken, 466-8560, Japan
Contact
-
Miyakonojo Shinsei Hospital
RECRUITINGMiyakonojō, Miyazaki, 885-0093, Japan
Contact Phone: •••-•••-••••
-
Miyazaki Prefectural Miyazaki Hospital
RECRUITINGMiyazaki, 880-8510, Japan
Contact Phone: •••-•••-••••
-
Nagaokai Medical Corporation - Neyagawa Sanatorium
RECRUITINGNeyagawa, Osaka, 572-0854, Japan
Contact Phone: •••-•••-••••
-
Narimasu Kosei Hospital
RECRUITINGtabashi City, Tokyo, 175-0091, Japan
Contact Phone: •••-•••-••••
-
National Center of Neurology and Psychiatry
RECRUITINGKodaira, Tokyo, 187-8551, Japan
Contact Phone: •••-•••-••••
-
National Hospital Organization Maizuru Medical Center
RECRUITINGMaizuru, Kyoto, 625-8502, Japan
Contact Phone: •••-•••-••••
-
National Hospital Organization Shimofusa Psychiatric Medical Center
RECRUITINGMIdori-ku, Chiba-shi, Chiba, 266-0007, Japan
Contact Phone: •••-•••-••••
-
National Kohnodai Medical Center.
RECRUITINGIchikawa, Chiba, 272-8516, Japan
Contact Phone: •••-•••-••••
-
Okayama University Hospital
RECRUITINGOkayama, 700-8558, Japan
Contact Phone: •••-•••-••••
-
Okehazama Hospital
RECRUITINGToyoake, Aichi-ken, 470-1168, Japan
Contact Phone: •••-•••-••••
-
Osaka Medical and Pharmaceutical University Hospital
RECRUITINGTakatsuki, Osaka, 569-8686, Japan
Contact Phone: •••-•••-••••
-
Osaka Psychiatric Medical Center
RECRUITINGHirakata, Osaka, 573-0022, Japan
Contact Phone: •••-•••-••••
-
Rainbow and Sea Hospital
RECRUITINGKaratsu-shi, Saga-ken, 847-0031, Japan
Contact Phone: •••-•••-••••
-
Saitama Konan Hospital
RECRUITINGKumagaya, Saitama, 360-0114, Japan
Contact Phone: •••-•••-••••
-
Saitama Neuropsychitric Institute
RECRUITINGSaitama, 338-8577, Japan
Contact Phone: •••-•••-••••
-
Shin-Abuyama Hospital
RECRUITINGTakatsuki, Osaka, 569-1041, Japan
Contact Phone: •••-•••-••••
-
Shiranui Hospital
RECRUITINGOmuta, Fukuoka, 836-0004, Japan
Contact Phone: •••-•••-••••
-
Takeda General Hospital - Aizuwakamatsu
RECRUITINGAizu-Wakamatsu, Fukushima, 965-0876, Japan
Contact Phone: •••-•••-••••
-
Toho University Omori Medical Center
RECRUITINGŌta-ku, Tokyo, 143-8541, Japan
Contact Phone: •••-•••-••••
-
Tokushima University Hospital
RECRUITINGTokushima, 770-8503, Japan
Contact Phone: •••-•••-••••
-
Tokyo Metropolitan Matsuzawa Hospital
RECRUITINGSetagaya City, Tokyo, 1560057, Japan
Contact Phone: •••-•••-••••
-
Tsurumi Nishii Hospital
RECRUITINGYokohama, Kanagawa, 230-0074, Japan
Contact Phone: •••-•••-••••
-
University Hospital,Kyoto Prefectural University of Medicine
RECRUITINGKyoto, 602-8566, Japan
Contact Phone: •••-•••-••••
-
University of the Ryukyus Hospital
RECRUITINGGinowan, Okinawa, 901-2725, Japan
Contact Phone: •••-•••-••••
-
Wakayama Medical University Hospital
RECRUITINGWakayama, 641-8510, Japan
Contact Phone: •••-•••-••••
-
Yamagata Sakuracho Hospital
RECRUITINGYamagata, 990-0045, Japan
Contact Phone: •••-•••-••••
-
Yamaguchi University Hospital
RECRUITINGUbe, Yamaguchi, 755-8505, Japan
Contact Phone: •••-•••-••••
-
Yokohama City University Medical Center
RECRUITINGYokohama, Kanagawa, 232-0024, Japan
Contact Phone: •••-•••-••••
-
Yuge Hospital
RECRUITINGKumamoto, Kumamoto, 861-8002, Japan
Contact Phone: •••-•••-••••