New hope for schizophrenia: KarXT shows promise in major trial
NCT ID NCT05919823
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a new drug called KarXT in 202 Chinese adults hospitalized for schizophrenia. The goal was to see if KarXT could reduce symptoms like hallucinations and delusions better than a placebo over 5 weeks, followed by a 12-week period where everyone received the drug. The trial is complete, and results will show if KarXT is a safe and effective option for managing this serious mental illness.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Anhui Mental Health Center
Hefei, Anhui, 230022, China
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Beijing Anding Hospital Capital Medical University
Beijing, Beijing Municipality, 100035, China
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Beijing HuiLongGuan Hospital
Changping, Beijing Municipality, 100096, China
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Chongqing 11th People's Hospital
Chongqing, Chongqing Municipality, 400047, China
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Chongqing Mental Health Center
Jiangbei, Chongqing Municipality, 401147, China
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Daqing City Third Hospital
Daqing, Heilongjiang, 163161, China
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Guangyuan Mental Health Center
Guangyuan, Sichuan, 628033, China
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Hangzhou Seventh People's Hospital
Hangzhou, Zhejiang, 310013, China
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HuZhou Third Municipal Hospital
Huzhou, Zhejiang, 313028, China
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Jiangxi Mental Health Center
Nanchang, Jiangxi, 330027, China
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Mental Health Center of Xi'an City
Xi'an, Shaanxi, 710061, China
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Ningbo Kangning Hospital
Ningbo, Zhejiang, 315002, China
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Peking University Sixth Hospital
Beijing, Beijing Municipality, 100083, China
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Renmin Hospital of Wuhan University
Wuhan, Hubei, 430064, China
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Shandong Daizhuang Hospital
Jining, Shandong, 272009, China
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Shandong Mental Health Center
Jinan, Shandong, 250014, China
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Shanghai Mental Health Center
Shanghai, Shanghai Municipality, 200032, China
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The Affiliated Brain Hospital of Guangzhou Medical University
Guanzhou, Guangdong, 510370, China
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The First Affiliated Hospital of Wenzhou Medical University
Wenzhou, Zhejiang, 325015, China
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The Fourth People's Hospital of Chengdu
Chengdu, Sichuan, 610036, China
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The Second Xiangya Hospital of Central South University
Changsha, Hunan, 410011, China
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The Sixth People's Hosptial of Hebei Province
Baoding, Hebei, 071051, China
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Tianjin Anding Hospital
Tianjin, Tianjin Municipality, 300382, China
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Urumqi Fourth People's Hospital
Ürümqi, Xinjiang, 830002, China
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Wuhan Mental Health Center
Wuhan, Hubei, 430000, China
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Wuhu Hospital of Beijing Anding Hospital
Wuhu, Anhui, 241000, China
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Wuxi Mental Health Center
Wuxi, Jiangsu, 214151, China
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Zhumadian Second People's Hospital
Zhumadian, Henan, 463001, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Could a new pill for schizophrenia pass its first human test?
- Can a new daily pill offer safer Long-Term control of schizophrenia?
- Can an Anti-Seizure drug quiet the brain and sharpen thinking in schizophrenia?
- Can a dissolving film tame agitation in schizophrenia?
- Can a phone app teach the brain to read social cues?
- Can a gentle brain current silence voices that medication Can't?