New hope for schizophrenia: KarXT shows promise in major trial
NCT ID NCT05919823
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a new drug called KarXT in 202 Chinese adults hospitalized for schizophrenia. The goal was to see if KarXT could reduce symptoms like hallucinations and delusions better than a placebo over 5 weeks, followed by a 12-week period where everyone received the drug. The trial is complete, and results will show if KarXT is a safe and effective option for managing this serious mental illness.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Anhui Mental Health Center
Hefei, Anhui, 230022, China
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Beijing Anding Hospital Capital Medical University
Beijing, Beijing Municipality, 100035, China
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Beijing HuiLongGuan Hospital
Changping, Beijing Municipality, 100096, China
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Chongqing 11th People's Hospital
Chongqing, Chongqing Municipality, 400047, China
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Chongqing Mental Health Center
Jiangbei, Chongqing Municipality, 401147, China
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Daqing City Third Hospital
Daqing, Heilongjiang, 163161, China
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Guangyuan Mental Health Center
Guangyuan, Sichuan, 628033, China
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Hangzhou Seventh People's Hospital
Hangzhou, Zhejiang, 310013, China
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HuZhou Third Municipal Hospital
Huzhou, Zhejiang, 313028, China
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Jiangxi Mental Health Center
Nanchang, Jiangxi, 330027, China
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Mental Health Center of Xi'an City
Xi'an, Shaanxi, 710061, China
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Ningbo Kangning Hospital
Ningbo, Zhejiang, 315002, China
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Peking University Sixth Hospital
Beijing, Beijing Municipality, 100083, China
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Renmin Hospital of Wuhan University
Wuhan, Hubei, 430064, China
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Shandong Daizhuang Hospital
Jining, Shandong, 272009, China
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Shandong Mental Health Center
Jinan, Shandong, 250014, China
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Shanghai Mental Health Center
Shanghai, Shanghai Municipality, 200032, China
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The Affiliated Brain Hospital of Guangzhou Medical University
Guanzhou, Guangdong, 510370, China
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The First Affiliated Hospital of Wenzhou Medical University
Wenzhou, Zhejiang, 325015, China
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The Fourth People's Hospital of Chengdu
Chengdu, Sichuan, 610036, China
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The Second Xiangya Hospital of Central South University
Changsha, Hunan, 410011, China
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The Sixth People's Hosptial of Hebei Province
Baoding, Hebei, 071051, China
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Tianjin Anding Hospital
Tianjin, Tianjin Municipality, 300382, China
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Urumqi Fourth People's Hospital
Ürümqi, Xinjiang, 830002, China
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Wuhan Mental Health Center
Wuhan, Hubei, 430000, China
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Wuhu Hospital of Beijing Anding Hospital
Wuhu, Anhui, 241000, China
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Wuxi Mental Health Center
Wuxi, Jiangsu, 214151, China
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Zhumadian Second People's Hospital
Zhumadian, Henan, 463001, China