Could KarXT be the key to treating teen schizophrenia?

NCT ID NCT07288567

Recruiting now Disease control Sponsor: Bristol-Myers Squibb Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jul 01, 2026 · Updated 3 times

Summary

This phase 3 trial is testing whether the drug KarXT can safely and effectively treat schizophrenia in adolescents aged 13 to 17. About 166 teens will receive either KarXT or a placebo, and researchers will track changes in symptoms like delusions and social withdrawal. The goal is to see if KarXT offers a new treatment option for this age group.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

KarXT (also known as BMS-986510)

What this could lead to

If it works, this could offer a new treatment option for teenagers with schizophrenia, potentially easing symptoms like hallucinations and social withdrawal.

What could go wrong

This is still a clinical trial, so it's not proven yet. The drug may not work better than a placebo, and side effects are possible. Results may not apply to all teens.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

schizophrenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SCHIZOPHRENIA

Contacts and locations

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Study contacts

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Phone: •••-•••-•••• Email: •••••@•••••
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Locations

Advanced Research Center Inc.
RECRUITING

Anaheim, California, 92805, United States

Contact Phone: •••-•••-••••
Apg Research, Llc
RECRUITING

Orlando, Florida, 32803, United States

Contact Phone: •••-•••-••••
Atlanta Center for Medical Research
RECRUITING

Atlanta, Georgia, 30331, United States

Contact Phone: •••-•••-••••
Denali Health Atlanta, LLC
RECRUITING

Stone Mountain, Georgia, 30083, United States

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EmVenio Research Center - Prime Healthcare
RECRUITING

Chicago, Illinois, 60622, United States

Contact Phone: •••-•••-••••
Goryokai Medical Corporation - Goryokai Hospital
RECRUITING

Sapporo, Hokkaido, 002-8029, Japan

Contact Phone: •••-•••-••••
Inland Psychiatric Medical Group.
RECRUITING

Chino, California, 91710, United States

Contact Phone: •••-•••-••••
Local Institution - 0001
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Barranquilla, 080020, Colombia

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Local Institution - 0008
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Iași, 700282, Romania

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Local Institution - 0009
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Pereira, Risaralda Department, 660003, Colombia

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Local Institution - 0020
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Bogotá, 111166, Colombia

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Local Institution - 0024
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Culver City, California, 90230, United States

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Local Institution - 0025
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Zentsujichó, Kagawa-ken, 765-8507, Japan

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Local Institution - 0029
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Bucharest, Bucharest, 041914, Romania

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Local Institution - 0030
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Sibiu, 550082, Romania

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Local Institution - 0031
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Cluj-Napoca, 400370, Romania

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Local Institution - 0035
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Córdoba, X5003DCE, Argentina
Local Institution - 0036
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Buenos Aires, C1405BOA, Argentina
Local Institution - 0038
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Timișoara, 300329, Romania

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Bucharest, 021056, Romania

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Bucharest, 031871, Romania

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Garland, Texas, 75043, United States

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Richmond, Virginia, 23284, United States

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Local Institution - 0056
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Ōta-ku, Tokyo, 1438541, Japan

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Local Institution - 0059
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Worcester, Massachusetts, 01608, United States

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Local Institution - 0061
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Great Neck, New York, 11021, United States

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Local Institution - 0062
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Miyakonojō, Miyazaki, 885-0093, Japan

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Local Institution - 0063
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Yokohama, Kanagawa, 213-8507, Japan

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Local Institution - 0066
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Spring, Texas, 77381, United States

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Local Institution - 0075
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Chikugo-Shi, Fukuoka, 833-0041, Japan

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Local Institution - 0076
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Boston, Massachusetts, 02115, United States

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Local Institution - 0083
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Redlands, California, 92373, United States

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Local Institution - 0084
WITHDRAWN

Ciudad Autónoma de Buenos Aires, Buenos Aires, C1133AAH, Argentina
Local Institution - 0085
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La Plata, Buenos Aires, 1900, Argentina
Local Institution - 0086
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Bunkyo-ku, Tokyo, 113-8431, Japan

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Local Institution - 0089
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San Francisco, California, 94158, United States

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Local Institution - 0102
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Santiago del Estero, 4200, Argentina
Local Institution - 0109
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Bello, Antioquia, 051053, Colombia

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Local Institution - 0113
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Nashville, Tennessee, 37212, United States

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Local Institution - 0118
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Plano, Texas, 75093, United States

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Local Institution - 0119
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Hollywood, Florida, 33024, United States

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Local Institution - 0120
NOT_YET_RECRUITING

Houston, Texas, 77043, United States

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Salveo Integrative Health - Lawrenceville
RECRUITING

Lawrenceville, Georgia, 30046, United States

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University of Cincinnati Dept of Psychiatry and Behavioral Neuroscience
RECRUITING

Cincinnati, Ohio, 45219, United States

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