Can a diuretic shield kidneys from contrast dye in heart failure?

NCT ID NCT07550790

Recruiting now Disease control Sponsor: Jin Joo Park Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jul 17, 2026 · Updated 3 times

Summary

This study tests whether giving a diuretic (furosemide) to reduce fluid buildup can better protect the kidneys from contrast dye damage compared to standard IV fluids. It involves 190 adults hospitalized with acute heart failure and moderate kidney problems who need a CT scan. Researchers will measure kidney function before and after the scan to see which approach works best.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Furosemide and normal saline
What this could lead to: If successful, this could show a better way to protect kidneys during contrast scans in heart failure patients, reducing the risk of acute kidney injury.
What could go wrong: This is a small, early-stage trial (190 participants) testing a strategy, not a new drug. The results may not apply to all patients, and the decongestion approach could cause dehydration or electrolyte imbalances.

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Conditions

The condition(s) this trial relates to.

heart failure impaired renal function disease kidney failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEART FAILURE, ACUTE RENAL DYSFUNCTION

Contacts and locations

Locations

Seoul National University Bundang Hospital
RECRUITING

Seongnam-si, Gyeonggi-do, 13620, South Korea

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