Urine test could guide heart failure treatment and save lives
NCT ID NCT06092437
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether using urine sodium levels to adjust diuretic doses helps people with acute heart failure recover faster and live longer. About 556 adults hospitalized with acute heart failure will receive either standard care or a tailored diuretic plan. The goal is to see if this approach reduces deaths, heart failure events, and improves quality of life.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
loop diuretics (furosemide) and other diuretics (thiazide, MRA, acetazolamide)
What this could lead to
If it works, this could lead to a more effective way to treat fluid buildup in acute heart failure, potentially reducing deaths and hospital visits.
What could go wrong
This is a mid-sized trial testing a treatment algorithm, not a new drug. The approach may not improve outcomes or could cause kidney issues. Results are not guaranteed.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Amphia ziekenhuis
RECRUITINGBreda, North Brabant, 4818 CK, Netherlands
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Zuyderland MC
RECRUITINGHeerlen, Limburg, 6419 PC, Netherlands
Contact Phone: •••-•••-••••
Contact Phone: •••-•••-••••