New drug combo aims to fight tough breast cancer

NCT ID NCT07045311

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This Phase 2 trial tests two different drug combinations—JS207 plus 9MW2821 or JS207 plus albumin paclitaxel—as a first treatment for people with recurrent or metastatic triple-negative breast cancer. The study will enroll 80 participants to see if these combinations can shrink tumors and control the disease. Researchers will also monitor side effects and how long the benefits last.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

JS207 combined with 9MW2821 or albumin paclitaxel

What this could lead to

If successful, this could offer a new first-line treatment option for people with advanced triple-negative breast cancer, potentially improving tumor shrinkage and delaying disease progression.

What could go wrong

This is an early Phase 2 trial with only 80 participants, so results may not apply to everyone. The combination therapies may cause side effects, and there is no guarantee they will work better than existing treatments.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

triple-negative breast carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Affiliated Hospital of Hebei University

    RECRUITING

    Baoding, Hebei, 071030, China

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Affiliated Tumor Hospital of Xinjiang Medical University

    RECRUITING

    Ürümqi, Xinjiang Uygur Autonomous Region, 830000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Anhui Provincial Cancer Hospital

    NOT_YET_RECRUITING

    Hefei, Anhui, 230000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Ceneral Hosipital of Ningxia Medical University

    NOT_YET_RECRUITING

    Yinchuan, Ningxia, 750000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Guangdong women and children's hospital and health institute

    NOT_YET_RECRUITING

    Guangzhou, Guangdong, 511400, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Harbin Medical University Affiliated Cancer Hospital

    NOT_YET_RECRUITING

    Harbin, Heilongjiang, 150001, China

  • Harbin Medical University Affiliated Cancer Hospital

    NOT_YET_RECRUITING

    Harbin, Heilongjiang, 150001, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Henan Cancer Hospital

    RECRUITING

    Zhangzhou, Henan, 450003, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Hubei Cancer Hospital

    RECRUITING

    Wuhan, Hubei, 430079, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Jiangsu Cancer Hospital

    RECRUITING

    Nanjing, Jiangsu, 210009, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Jiangsu Province Hospital

    NOT_YET_RECRUITING

    Nanjing, Jiangsu, 210029, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Jilin University First Hospital

    RECRUITING

    Changchun, Jilin, 130021, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Liaoning Cancer Hospital&Institute

    RECRUITING

    Shenyang, Liaoning, 110801, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Nanchang People'S Hospital

    NOT_YET_RECRUITING

    Nanchang, Jiangxi, 330000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Peking University People's Hospital

    RECRUITING

    Beijing, Beijing Municipality, 100044, China

    Contact

    Contact

  • The Affiliated Hospital of Qingdao University

    RECRUITING

    Qingdao, Shandong, 266035, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • The Fifth Medical Center of PLA General Hospital

    RECRUITING

    Beijing, Beijing Municipality, 100071, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • The First Affiliated Hospital of Xi'an Jiaotong University

    RECRUITING

    Xian, Shanxi, 710061, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • The First Hospital of China Medical University

    RECRUITING

    Shenyang, Liaoning, 110002, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • The Second Affiliated Hospital Zhejiang University School of Medicine

    NOT_YET_RECRUITING

    Hangzhou, Zhejiang, 310000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • The Second Hospital of Dalian Medical University

    RECRUITING

    Dalian, Liaoning, 116027, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Xi'an International Medical Center Hospital

    RECRUITING

    Xian, Shanxi, 710100, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact