New depression pill aims to lift mood in just days

NCT ID NCT06785012

Recruiting now Symptom relief Sponsor: Janssen Research & Development, LLC Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated May 02, 2026 · Updated 23 times

Summary

This study tests an experimental drug called JNJ-89495120 to see if it can quickly reduce depression symptoms in adults with major depressive disorder. About 124 participants will receive either the drug or a placebo, and researchers will measure mood changes using a standard depression scale. The goal is to find a fast-acting treatment option for people who have had depression before.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

ATP Clinical Research
RECRUITING

Orange, California, 92866, United States
Accelerated Clinical Research Group LLC
RECRUITING

Snellville, Georgia, 30078, United States
Advanced Research Institute of Miami
COMPLETED

Homestead, Florida, 33030, United States
Alpine Research Organization
RECRUITING

Clinton, Utah, 84015, United States
Anderson Clinical Research
RECRUITING

Redlands, California, 92374, United States
Artemis Institute for Clinical Research
COMPLETED

San Diego, California, 92103, United States
Best Choice Medical and Research Service
COMPLETED

Pembroke Pines, Florida, 33024, United States
CBH Health
COMPLETED

Gaithersburg, Maryland, 20877, United States
CI Trials
RECRUITING

Bellflower, California, 90706, United States
Chandler Clinical Trials
COMPLETED

Chandler, Arizona, 85224, United States
Coastal Carolina Research Center
COMPLETED

North Charleston, South Carolina, 29405, United States
Core Clinical Research
RECRUITING

Everett, Washington, 98201, United States
DelRicht Research
COMPLETED

New Orleans, Louisiana, 70115, United States
Gulfcoast Medical Research Center
COMPLETED

Fort Myers, Florida, 33912, United States
Health Synergy Clinical Research
RECRUITING

West Palm Beach, Florida, 33407, United States
IMA Clinical Research PC Phoenix
COMPLETED

Phoenix, Arizona, 85012, United States
Indiana University IU Health
RECRUITING

Indianapolis, Indiana, 46202, United States
Inland Psychiatric Medical Group Inc
RECRUITING

Temecula, California, 92591, United States
Integrative Clinical Trials LLC
RECRUITING

Brooklyn, New York, 11229, United States
Interventional Psychiatry of Tampa Bay
RECRUITING

Tampa, Florida, 33629, United States
K2 Medical Research
RECRUITING

Maitland, Florida, 32751, United States
Lumos Clinical Research Center LLC
RECRUITING

San Jose, California, 95124, United States
Mountain View Clinical Research
COMPLETED

Denver, Colorado, 80209, United States
National Institute Of Clinical Research
COMPLETED

Garden Grove, California, 92844, United States
Noble Clinical Research
COMPLETED

Tucson, Arizona, 85704, United States
OSU Department of Psychiatry and Behavioral Health
RECRUITING

Columbus, Ohio, 43210, United States
Paradigm Research Professionals, LLC
RECRUITING

Oklahoma City, Oklahoma, 73116, United States
Patient Priority Clinical Sites LLC
RECRUITING

Cincinnati, Ohio, 45215, United States
Pharmax Research Clinic Inc
RECRUITING

Miami, Florida, 33126, United States
Revival Research Institute LLC
RECRUITING

McKinney, Texas, 75071, United States
Sunwise Clinical Research
RECRUITING

Walnut Creek, California, 94596, United States
Synexus Clinical Research US Inc
RECRUITING

Atlanta, Georgia, 30328, United States
Syrentis Clinical Research
RECRUITING

Santa Ana, California, 92705, United States
The Medici Medical Research
RECRUITING

Hollywood, Florida, 33021, United States
UAB Huntsville Regional Medical Campus
RECRUITING

Huntsville, Alabama, 35801, United States
University of Arizona
RECRUITING

Tucson, Arizona, 85724, United States
University of Chicago Medical Center
RECRUITING

Chicago, Illinois, 60637, United States
University of Cincinnati
RECRUITING

Cincinnati, Ohio, 45219, United States
University of Massachusetts Medical School
RECRUITING

Worcester, Massachusetts, 01655, United States
University of Pennsylvania
RECRUITING

Philadelphia, Pennsylvania, 19104, United States
WR-Newport Beach
COMPLETED

Newport Beach, California, 92660, United States
Wake Research PRI Encino
RECRUITING

Encino, California, 91316, United States
Wellness Research Center
RECRUITING

Miami, Florida, 33135, United States
iResearch Atlanta LLC
RECRUITING

Decatur, Georgia, 30030, United States

Conditions

Explore the condition pages connected to this study.

DEPRESSIVE DISORDER, MAJOR