New Crohn's drug shows promise in major trial

NCT ID NCT07577843

Recruiting now Disease control Sponsor: Janssen Research & Development, LLC Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 07, 2026 · Updated 2 times

Summary

This study tests a new medicine, JNJ-78934804, against an existing drug (guselkumab) in 460 people with moderate-to-severe Crohn's disease. The goal is to see if the new drug can reduce symptoms and heal the gut lining better at 48 weeks. Participants must have had Crohn's for at least 12 weeks and have active disease. This is a long-term treatment, not a cure.

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Conditions

The condition(s) this trial relates to.

Crohn disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CROHN DISEASE

Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Bezmialem University Medical Faculty
RECRUITING

Istanbul, 34093, Turkey (Türkiye)
Bnai Zion Medical Center
RECRUITING

Haifa, 31048, Israel
Clinnova Research
RECRUITING

Anaheim, California, 92805, United States
GCP Clinical Research
RECRUITING

Tampa, Florida, 33609, United States
GI Research Institute (G.I.R.I.)
RECRUITING

Vancouver, British Columbia, V6Z 2K5, Canada
Gastro SB Clinic
RECRUITING

Chula Vista, California, 91910, United States
Hokkaido P.W.F.A.C. Sapporo-Kosei General Hospital
RECRUITING

Sapporo, 060-0033, Japan
IBD SA
RECRUITING

Kurralta Park, 5037, Australia
Japanese Red Cross Kumamoto Hospital
RECRUITING

Kumamoto, 861-8520, Japan
Japanese Red Cross Osaka Hospital
RECRUITING

Osaka, 543-8555, Japan
Kagoshima IBD Gastroenterology Clinic
RECRUITING

Kagoshima, 892-0843, Japan
Kocaeli University Medical Faculty
RECRUITING

Kocaeli, 41001, Turkey (Türkiye)
London Digestive Disease Institute
RECRUITING

London, Ontario, N6K 1M6, Canada
Meir Medical Center
RECRUITING

Kfar Saba, 44281, Israel
Mersin University Medical Faculty
RECRUITING

Mersin, 33343, Turkey (Türkiye)
National Hospital Organization Hirosaki National Hospital
RECRUITING

Hirosaki, 036-8545, Japan
New York Gastroenterology Associates
RECRUITING

New York, New York, 10075, United States
Peak Gastroenterology Associates
RECRUITING

Colorado Springs, Colorado, 80907, United States
Rambam Medical Center
RECRUITING

Haifa, 3109601, Israel
Sanchez Clinical Research, Inc
RECRUITING

Miami, Florida, 33157-6575, United States
Sheba Medical Center
RECRUITING

Ramat Gan, 52621, Israel
Tel Aviv Sourasky Medical Center
RECRUITING

Tel Aviv, 64239, Israel

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