New hope for Hard-to-Treat lung cancer: experimental drug combo enters trial

NCT ID NCT07207395

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests an experimental drug called JBI-802, either alone or with the immunotherapy pembrolizumab, in 30 adults with advanced lung cancer that has a specific genetic change (STK11 mutation). The main goals are to check safety and see if the treatment can shrink tumors or slow cancer growth.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

JBI-802 (an experimental drug) and pembrolizumab (an immunotherapy)

What this could lead to

If successful, this could offer a new treatment option for people with a specific type of lung cancer that has few effective therapies.

What could go wrong

This is an early Phase 2 trial with only 30 participants, so results may not apply broadly. The drug combination may cause side effects or fail to shrink tumors.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

lung cancer lung neoplasm non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The Christ Hospital

    RECRUITING

    Cincinnati, Ohio, 45219, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact