New hope for myeloma patients: switching to ixazomib after failed treatments?

NCT ID NCT05013190

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study follows 72 adults with multiple myeloma who switch from a bortezomib- or carfilzomib-based treatment to an ixazomib-based regimen. Researchers are tracking side effects and how long patients go without the disease getting worse. The goal is to see if this switch is a good option in real-world settings.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

ixazomib (NINLARO®)

What this could lead to

If successful, this study could show that switching to ixazomib is a safe and effective option for multiple myeloma patients who have already tried bortezomib or carfilzomib.

What could go wrong

This is an observational study, not a controlled trial, so results may not prove cause and effect. It is also small (72 participants) and focused on Chinese patients, so findings may not apply to other populations.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

plasma cell myeloma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Affiliated Hospital of Inner Mongolia Medical University

    Hohhot, Inner Mongolia, 010050, China

  • Anhui Cancer Hospital

    Hefei, Anhui, 230000, China

  • Beijing Chao-Yang Hospital,Capital Medical University

    Beijing, Beijing Municipality, 100020, China

  • Beijing Jishuitan Hospital

    Beijing, Beijing Municipality, 100096, China

  • Henan Province People Hospital

    Zhengzhou, Henan, 450004, China

  • Qingdao Municipal Hospital

    Qingdao, Qingdao, 266071, China

  • Shengjing Hospital affiliated to China Medical University

    Shenyang, Liaoning, 110022, China

  • The First Affiliated Hospital of Nanchang University

    Nanchang, Jiangxi, 330006, China

  • The First Affiliated Hospital of Soochow University

    Suzhou, Jiangsu, 215006, China

  • The First Affiliated Hospital of Zhenzhou University

    Zhengzhou, Henan, 450052, China

  • Tianjin Medical University General Hospital

    Tianjin, Tianjin Municipality, 300052, China

  • West China Hospital, Sichuan University

    Chengdu, Sichuan, 610000, China