New implant could replace monthly shots for opioid addiction
NCT ID NCT07064564
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-stage trial tests a new naltrexone implant (iSTEP-N) that slowly releases medication over 12 months to block opioids. It will enroll 33 healthy adults and compare two implant doses to standard monthly injections. The goal is to see if the implant can maintain steady drug levels and be a more convenient treatment option.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
naltrexone implant
What this could lead to
If successful, this implant could provide a more convenient, long-lasting treatment option for opioid use disorder, reducing the need for monthly injections.
What could go wrong
This is an early Phase 1 study with only 33 healthy volunteers, so it may not show the expected drug levels or safety profile. The implant might not work as well as hoped, and side effects are still being studied.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
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