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Could a natural pill prevent blood clots in ovarian cancer patients?

NCT ID NCT07303894

Recruiting now Disease control Sponsor: Memorial Sloan Kettering Cancer Center Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jul 30, 2026 · Updated 3 times

Summary

This study tests whether a daily pill called isoquercetin, made from a plant compound, can reduce blood markers linked to clot risk in people with ovarian cancer. About 90 participants receiving chemotherapy will take either isoquercetin or a placebo for up to 6 weeks. The goal is to see if the drug lowers thrombin generation, a key step in clot formation.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
isoquercetin (a plant compound taken as a pill)
What this could lead to
If it works, this could point toward a way to lower the risk of dangerous blood clots in people with ovarian cancer.
What could go wrong
This is an early phase 2 trial with only 90 participants, so results may not apply to everyone. The study measures blood markers, not actual clot prevention, and it's possible isoquercetin won't work better than a placebo.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Carcinoma, Ovarian Epithelial ovarian cancer ovarian carcinoma ovarian clear cell tumor ovarian serous tumor

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

EPITHELIAL OVARIAN CANCER OVARIAN CANCER SEROUS OVARIAN TUMOR

Contacts and locations

Locations

  • Beth Israel Deaconess Medical Center (Data Collection Only)

    NOT_YET_RECRUITING

    Boston, Massachusetts, 02215, United States

  • Memorial Sloan Kettering Basking Ridge (All Protocol Activities)

    RECRUITING

    Basking Ridge, New Jersey, 07920, United States

  • Memorial Sloan Kettering Bergen (All Protocol Activities)

    RECRUITING

    Montvale, New Jersey, 07645, United States

  • Memorial Sloan Kettering Cancer Center (All Protocol Activites)

    RECRUITING

    New York, New York, 10065, United States

  • Memorial Sloan Kettering Monmouth (All Protocol Activities)

    RECRUITING

    Middletown, New Jersey, 07748, United States

  • Memorial Sloan Kettering Nassau (All protocol activities)

    RECRUITING

    Rockville Centre, New York, 11553, United States

  • Memorial Sloan Kettering Suffolk-Commack (All Protocol Activities )

    RECRUITING

    Commack, New York, 11725, United States

  • Memorial Sloan Kettering Westchester (All Protocol Activities)

    RECRUITING

    Harrison, New York, 10604, United States

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