New drug combo aims to halt smoldering myeloma before it strikes

NCT ID NCT02960555

First seen Nov 01, 2025 · Last updated Jun 15, 2026 · Updated 33 times

Summary

This study tests whether the drug isatuximab, given alone or with lenalidomide, can control high risk smoldering multiple myeloma and delay progression to active disease. About 61 participants will receive treatment and be monitored for response and side effects. The goal is to find a better way to manage this early, pre-cancerous condition.

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Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States

  • Mount Sinai Hospital

    New York, New York, 10029, United States

Conditions

Explore the condition pages connected to this study.