Lower-dose combo aims to tame myeloma without harsh side effects

NCT ID NCT05145400

First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 24 times

Summary

This study tests whether lower doses of three drugs (isatuximab, lenalidomide, and dexamethasone) can safely and effectively treat newly diagnosed multiple myeloma in patients who are very likely to have severe side effects from standard treatment. The goal is to reduce side effects while still controlling the cancer. About 50 participants will take part, and the study is currently recruiting.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Duke Comprehensive Cancer Center

    RECRUITING

    Durham, North Carolina, 27710, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Levine Cancer Institute

    RECRUITING

    Charlotte, North Carolina, 28204, United States

    Contact

  • Novant Health New Hanover Regional Medical Center

    RECRUITING

    Wilmington, North Carolina, 28401, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • The Ohio State University Comprehensive Cancer Center

    RECRUITING

    Columbus, Ohio, 43210, United States

    Contact Email: •••••@•••••

    Contact

  • University of North Carolina at Chapel Hill, Lineberger Comprehensive Cancer Center

    RECRUITING

    Chapel Hill, North Carolina, 27599, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.