Glow-in-the-Dark dye could prevent surgical blunders

NCT ID NCT05954767

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a dye called IS-001 that is injected into the blood to make the ureters (tubes from kidney to bladder) glow under a special camera during robotic gynecological surgery. The goal was to help surgeons see the ureters more clearly and avoid accidentally injuring them. 189 women scheduled for robotic surgery took part. The dye's effectiveness was measured by how well independent reviewers could see the ureters with the dye versus standard white light.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

IS-001 (a dye injected into the vein to make ureters glow under special light)

What this could lead to

If it works, this could help surgeons avoid accidentally injuring the ureters during gynecological surgery, making the procedure safer.

What could go wrong

This trial is already completed, but the results are not yet widely known. The dye may not improve visibility enough to change surgical outcomes, and there could be allergic reactions or other side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • E.W. Sparrow Hospital

    Lansing, Michigan, 48912, United States

  • HCA Mercy Hospital

    Miami, Florida, 33133, United States

  • Hoag Memorial Hospital Presbyterian

    Newport Beach, California, 92663, United States

  • MountainView Hospital

    Las Vegas, Nevada, 89128, United States

  • OhioHealth

    Columbus, Ohio, 43214, United States

  • Orlando Health

    Orlando, Florida, 32806, United States

  • St. David's Surgical Hospital

    Austin, Texas, 78681, United States

  • The Ohio State Unversity

    Columbus, Ohio, 43210, United States