Glow-in-the-Dark dye could prevent surgical blunders
NCT ID NCT05954767
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a dye called IS-001 that is injected into the blood to make the ureters (tubes from kidney to bladder) glow under a special camera during robotic gynecological surgery. The goal was to help surgeons see the ureters more clearly and avoid accidentally injuring them. 189 women scheduled for robotic surgery took part. The dye's effectiveness was measured by how well independent reviewers could see the ureters with the dye versus standard white light.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- IS-001 (a dye injected into the vein to make ureters glow under special light)
- What this could lead to
- If it works, this could help surgeons avoid accidentally injuring the ureters during gynecological surgery, making the procedure safer.
- What could go wrong
- This trial is already completed, but the results are not yet widely known. The dye may not improve visibility enough to change surgical outcomes, and there could be allergic reactions or other side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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E.W. Sparrow Hospital
Lansing, Michigan, 48912, United States
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HCA Mercy Hospital
Miami, Florida, 33133, United States
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Hoag Memorial Hospital Presbyterian
Newport Beach, California, 92663, United States
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MountainView Hospital
Las Vegas, Nevada, 89128, United States
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OhioHealth
Columbus, Ohio, 43214, United States
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Orlando Health
Orlando, Florida, 32806, United States
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St. David's Surgical Hospital
Austin, Texas, 78681, United States
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The Ohio State Unversity
Columbus, Ohio, 43210, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Blue dye could help surgeons spot blocked ureters during operations
- New dye could help surgeons see and protect ureters during robotic colorectal surgery
- Blue dye could make Children's surgery safer
- Blue dye could make surgery safer by spotting hidden ureter injuries
- Glow-in-the-dark dye could save kidneys during surgery