Blue dye study aims to find the right washout volume for infected knee implants
NCT ID NCT07324954
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This pilot study is testing how much irrigation fluid is needed to clear contaminants during revision knee replacement surgery for infection. Surgeons will apply a blue dye to the knee joint and wash it out in measured steps until the dye is gone. The goal is to gather data to design a larger trial on the best irrigation strategy. Only 20 adults having knee replacement surgery (with or without infection) will take part.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Methylene blue dye (used as a marker, not a treatment)
- What this could lead to
- If successful, this study could help design a larger trial to determine the best irrigation volume for cleaning infected knee replacements during surgery.
- What could go wrong
- This is a very small pilot study with only 20 participants, using a blue dye to mimic infection. The results may not apply to real infections or lead to any change in practice.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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UHealth Tower
RECRUITINGMiami, Florida, 33125, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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