Ultrasound-Guided injection may ease severe knee arthritis pain

NCT ID NCT06712394

Completed Symptom relief Sponsor: Sakarya University Source: ClinicalTrials.gov ↗

First seen Jul 06, 2026 · Last updated Jul 07, 2026 · Updated 1 time

Summary

This study tests whether an ultrasound-guided injection of local anesthetic into the space behind the knee (called the IPACK block) can reduce pain and improve function in people with advanced knee osteoarthritis. Researchers will measure pain, disability, and quality of life at one and three months after the injection. The goal is to see if this simple procedure can help those who have not found relief from other treatments.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: bupivacaine (local anesthetic)
What this could lead to: If effective, this nerve block could offer a non-surgical option to ease pain and improve mobility in people with advanced knee osteoarthritis.
What could go wrong: This is a small, observational study without a comparison group, so results may not prove the block works better than other treatments. Risks include temporary numbness or weakness, and the effect may not last long.

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Conditions

The condition(s) this trial relates to.

osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OSTEOARTHRITIS, KNEE

Contacts and locations

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Locations

Sakarya University

Adapazarı, Sakarya, 54010, Turkey (Türkiye)

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