New hope for fatal brain disease: drug trial begins

NCT ID NCT06153966

First seen Mar 22, 2026 · Last updated May 16, 2026 · Updated 13 times

Summary

This study tests a new drug called ION717 in 76 people with early-stage prion disease, a rare and fatal brain condition. The drug is given via a spinal injection to see if it is safe and how the body processes it. The goal is to slow or stop the disease, but participants will likely need ongoing treatment.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta

    RECRUITING

    Milan, 20133, Italy

  • Hospital Clinic De Barcelona

    RECRUITING

    Barcelona, 08036, Spain

  • Hôpital Universitaire Pitié Salpêtrière

    RECRUITING

    Paris, 75013, France

  • Massachusetts General Hospital

    RECRUITING

    Boston, Massachusetts, 02114, United States

  • McGill University Health Centre

    ACTIVE_NOT_RECRUITING

    Montreal, Quebec, H3A 2B4, Canada

  • Mihara Memorial Hospital

    ACTIVE_NOT_RECRUITING

    Gunma, Isesaki-shi, 372-0006, Japan

  • NYU Langone Health

    RECRUITING

    New York, New York, 10016, United States

  • National Center of Neurology and Psychiatry

    RECRUITING

    Tokyo, Kodaira-shi, 187-8551, Japan

  • Neuromuscular Center Yoshimizu Hospital

    RECRUITING

    Yamaguchi, Shimonoseki-shi, 751-0826, Japan

  • Royal Melbourne Hospital

    RECRUITING

    Parkville, 3050, Australia

  • Tel Aviv Sourasky Medical Center

    RECRUITING

    Tel Aviv, 6423906, Israel

  • University Hospitals Cleveland Medical Center

    RECRUITING

    Cleveland, Ohio, 44106, United States

  • University Medical Center Göttingen

    RECRUITING

    Göttingen, 37075, Germany

Conditions

Explore the condition pages connected to this study.