Experimental drug ION717 aims to slow fatal brain disease
NCT ID NCT06153966
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a new drug called ION717 for people with early-stage prion disease, a rare and fatal brain condition. The drug is given via a spinal injection and aims to reduce harmful prion proteins. The trial will check safety, side effects, and how the drug moves through the body. About 76 participants with a caregiver are needed.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
RECRUITINGMilan, 20133, Italy
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Hospital Clinic De Barcelona
RECRUITINGBarcelona, 08036, Spain
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Hôpital Universitaire Pitié Salpêtrière
RECRUITINGParis, 75013, France
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Massachusetts General Hospital
RECRUITINGBoston, Massachusetts, 02114, United States
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McGill University Health Centre
ACTIVE_NOT_RECRUITINGMontreal, Quebec, H3A 2B4, Canada
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Mihara Memorial Hospital
ACTIVE_NOT_RECRUITINGGunma, Isesaki-shi, 372-0006, Japan
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NYU Langone Health
RECRUITINGNew York, New York, 10016, United States
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National Center of Neurology and Psychiatry
RECRUITINGTokyo, Kodaira-shi, 187-8551, Japan
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Neuromuscular Center Yoshimizu Hospital
RECRUITINGYamaguchi, Shimonoseki-shi, 751-0826, Japan
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Royal Melbourne Hospital
RECRUITINGParkville, 3050, Australia
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Tel Aviv Sourasky Medical Center
RECRUITINGTel Aviv, 6423906, Israel
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University Hospitals Cleveland Medical Center
RECRUITINGCleveland, Ohio, 44106, United States
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University Medical Center Göttingen
RECRUITINGGöttingen, 37075, Germany