PRION DISEASE
Clinical trials for PRION DISEASE explained in plain language.
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New hope for fatal brain disease: drug trial begins
Disease control Recruiting nowThis study tests a new drug called ION717 in 76 people with early-stage prion disease, a rare and fatal brain condition. The drug is given via a spinal injection to see if it is safe and how the body processes it. The goal is to slow or stop the disease, but participants will lik…
Matched conditions: PRION DISEASE
Phase: PHASE1, PHASE2 • Sponsor: Ionis Pharmaceuticals, Inc. • Aim: Disease control
Last updated May 17, 2026 05:31 UTC
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First human trial of RNA therapy for fatal brain disease begins
Disease control Recruiting nowThis early-stage trial tests a new drug called PrP-siRNA in 30 adults with symptomatic prion disease, a rare and fatal brain condition. The drug is given via a spinal injection and aims to reduce levels of the harmful prion protein. The main goal is to check safety, but researche…
Matched conditions: PRION DISEASE
Phase: PHASE1 • Sponsor: Broad Institute of MIT and Harvard • Aim: Disease control
Last updated May 15, 2026 11:57 UTC